Theagr P2 operon: An autocatalytic sensory transduction system inStaphylococcus aureus

Springer Science and Business Media LLC - Tập 248 Số 4 - Trang 446-458 - 1995
Richard P. Novick1, Steven J. Projan, John Kornblum, Hope F. Ross, Guanghui Ji, Barry N. Kreiswirth, François Vandenesch, Soraya L. Moghazeh
1Public Health Research Institute of the City of New York, Inc., NY 10016, USA.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Abdelnour A, Arvidson S, Bremell T, Ruden C, Tarkowski A (1993) The accessory gene regulator (agr) controlsStaphylococcus aureus virulence in a murine arthritis model. Infect Immun 61:3879–3885

Arvidson S, Janzon L, Lofdahl S (1990) The role of the delta-lysin gene (hld) in theagr-dependent regulation of exoprotein synthesis inStaphylococcus aureus. In: Novick RP (ed) Molecular biology of the Staphylococci. VCH Publishers, New York, pp 421–432

Arvidson S, Janzon L, Lofdahl S, Morfeldt E (1989) The exoprotein regulatory regionexp ofS. aureus. In: Butler EO, Moseley EB (eds) Genetic transformation and expression. Intercept, Wimbourne, Dorset UK, Ltd 511–518

Arvidson SO (1983) Extracellular enzymes fromStaphylococcus aureus. In: Easmon CF, Adlam C (eds) Staphylococci and staphyloccocal infections. vol 2. Academic Press, London, pp 745–808

Balaban N, Novick RP (1995) Autocrine regulation of toxin synthesis byStaphylococcus aureus. Proc Natl Acad Sci USA 92:1619–1623

Bernheimer AW Schwartz LL (1963) Isolation and composition of staphylococcal alpha toxin. J Gen Microbiol 30:455–468

Bjorklind A, Arvidson S (1980) Mutants ofStaphylococcus aureus affected in the regulation of exoprotein synthesis. FEMS Microbiol Lett 7: 203–206

Connell N, Han Z, Moreno F, Kolter R (1987) AnE. coli promoter induced by the cessation of growth. Mol Microbiol 1:195–201

Engelman DM, Steitz TA, Goldman A (1986) Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins. Ann Rev Biophys Chem 15:321–353

Foster TJ, O'Reilly M, Phonimdaeng P, Cooney J, Patel AH, Bramley AJ (1990) Genetic studies of virulence factors ofStaphylococcus aureus. Properties of coagulase and gamma-toxin, alpha-toxin, beta-toxin and protein A in the pathogenesis ofS. aureus infections. In: Novick RP (ed) Molecular biology of the Staphylococci. VCH Publishers, New York, pp 403–420

Gennaro ML, Novick RP (1988) An enhancer of DNA replication. J Bacteriol 170:5709–5717

Gray GS, Kehoe M (1984) Primary sequence of the alpha-toxin gene fromStaphylococcus aureus wood 46. Infect Immun 46:615–618

Horinouchi S, Weisblum B (1982) Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance. J Bacteriol 150: 815–825

Janzon L, Arvidson S (1990) The role of the delta-lysin gene (hld) in the regulation of virulence genes by the accessory gene regulator (agr) inStaphylococcus aureus. EMBO J 9:1391–1399

Janzon L, Lofdahl S, Arvidson S (1989) Identification and nucleotide sequence of the delta-lysin gene,hld, adjacent to the accessory gene regulator (agr) ofStaphylococcus aureus. Mol Gen Genet 219:480–485

Kornblum J, Kreiswirth B, Projan S, Ross H, Novick RP (1990)Agr: a polycistronic locus regulating exoprotein synthesis inStaphylococcus aureus. Molecular biology of the Staphylococci. VCH Publishers, New York, NY, 373–402

Kreiswirth B, Lofdahl S, Bettey M, O'Reilly M, Schlievert P, Bergdoll M, Novick RP (1983) The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:709–712

Losick R, Youngman P, Piggot PJ (1986) Genetics of endospore formation inBacillus subtilis. Annu Rev Genet 20:625–669

Magasanik B (1982) Genetic control of nitrogen assimilation in bacteria. Annu Rev Genet 16:135–168

Mallonee DH, Glatz BA, Pattee P (1982) Chromosomal mapping of a gene affecting enterotoxin A production inStaphylococcus aureus. Appl Environ Microbiol 43:397–402

McLaughlin JR, Murray CL, Rabinowitz JC (1981) Unique features in the ribosome binding site sequence of the gram-positiveStaphylococcus aureus β-lactamase gene. J Biol Chem 256:11283–11291

Morfeldt E, Janzon L, Arvidson S, Lofdahl S (1988) Cloning of a chromosomal locus (exp) which regulates the expression of several exoprotein genes inStaphylococcus aureus. Mol Gen Genet 211:435–440

Nixon BT, Ronson CW, Ausubel FM (1986) Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genesntrB andntrC. Proc Natl Acad Sci USA 83:7850–7854

Novick R (1967) Properties of a cryptic high-frequency transducing phase inStaphylococcus aureus. Virology 33:155–166

Novick R, Kornblum J, Kreiswirth B, Projan S, Ross H (1989)Agr: a complex locus regulating post-exponential phase exoprotein synthesis inStaphylococcus aureus. In: Butler LO, Moseley, BEB (eds) Genetic transformation and expression. Intercept, Andover, Hants, UK, pp 495–510

Novick RP, Brodsky RJ (1972) Studies on plasmid replication: plasmid incompatibility and establishment inStaphylococcus aureus. J Mol Biol 68:285–302

Novick RP, Kornblum J (1990) Regulation of post-exponential phase exoprotein synthesis inStaphylococcus aureus. In: Ayoub EM (ed) Microbial determinants of virulence and host response. American Society for Microbiology, Washington, DC, pp 3–18

Novick RP, Ross HF, Projan SJ, Kornblum J, Kreiswirth B, Moghazeh S (1993) Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. EMBO J 12:3967–3975

O'Callaghan CH, Morris A, Kirby SM, Shingler AH (1972) Novel method for detection of β-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Ag Chemother 1: 283–288

Peng HL, Novick RP, Kreiswirth B, Kornblum J, Schlievert P (1988) Cloning, characterization and sequencing of an accessory gene regulator (agr) inStaphylococcus aureus. J Bacteriol 179:4365–4372

Projan SJ, Carleton S, Novick RP (1983) Determination of plasmid copy number by fluorescence densitometry. Plasmid 9:182–190

Ranellin DM, Jones CL, Johns MB, Mussey GJ, Khan SA (1985) Molecular cloning of staphylococcal enterotoxin B gene inEscherichia coli andStaphylococcus aureus. Proc Natl Acad Sci USA 82:5850–5854

Recsei P, Kreiswirth B, O'Reilly M, Schlievert P, Gruss A, Novick RP (1986) Regulation of exoprotein gene expression byagr. Mol Gen Genet 202:58–61

Ross H (1989) Molecular genetics of exoprotein regulation inStaphylococcus aureus. Doctoral dissertation. New York University

Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual (2nd edn) Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY

Sanger F, Coulson A, Barrell BG, Smith AJH, Roe BA (1980) Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol 143:161–178

Scarlato V, Arico B, Pragnola A, Rappuoli R (1989) Sequential activation and environmental regulation of virulence genes inBordetella pertussis. EMBO J 10: 3971–3975

Stock JB, Ninfa AJ, Stock AM (1989) Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol Rev 53:450–490

Vandenesch F, Projan S, Kreiswirth B, Etienne J, Novick RP (1993)Agr-related sequences inStaphylococcus lugdunensis. FEMS Microbiol Lett 111: 115–122

Wang PZ, Projan SJ, Leason K, Novick RP (1987) Translational fusion with a secretory enzyme as an indicator. J Bacteriol 169:3082–3087

Wyman L, Novick RP (1974) Studies on plasmid replication. IV. Complementation of replication-defective mutants by an incompatibility-deficient plasmid. Molec Gen Genet 135:149–161