Các đặc điểm độc đáo của rối loạn đông máu trong COVID-19
Tóm tắt
Các biến chứng do huyết khối và rối loạn đông máu thường xảy ra trong COVID-19. Tuy nhiên, các đặc điểm của rối loạn đông máu liên quan đến COVID-19 (CAC) khác biệt so với những gì thấy ở rối loạn đông máu do sốt xuất huyết vi khuẩn (SIC) và đông máu nội mạch lan tỏa (DIC), với CAC thường thể hiện mức D-dimer và fibrinogen tăng cao nhưng ban đầu chỉ có những bất thường tối thiểu về thời gian prothrombin và số lượng tiểu cầu. Huyết khối tĩnh mạch và huyết khối động mạch diễn ra thường xuyên hơn trong CAC so với SIC/DIC. Các đặc điểm lâm sàng và xét nghiệm của CAC có một số sự trùng lặp với hội chứng hemophagocytic, hội chứng chống phospholipid và viêm mạch huyết khối. Chúng tôi tóm tắt các đặc điểm chính của các rối loạn đông máu điển hình, thảo luận về sự tương đồng và khác biệt nhằm xác định đặc điểm độc đáo của CAC.
Từ khóa
Tài liệu tham khảo
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