The transmission of prions to humans

Wiley - Tập 88 Số s433 - Trang 28-32 - 1999
RG Will1
1National CJD Surveillance Unit, Western General Hospital, Edinburgh, UK

Tóm tắt

The identification of new‐variant Creutzfeldt‐Jakob disease (nvCJD) in 1996 led to the proposalhd that this new disease was caused by the transmission of bovine spongiform encephalopathy (BSE)ve epidemiologyof Creutzfeldt‐jakob disease in six to the human population. The ramifications of such a proposal have been extensive and profound,8; 43: 763–7 both politically and on the general public in the UK and other countries. Patients with nvCJD: 960–70 exhibit a consistent set of clinicopathological features, and cases of nvCJD continue to be reportedob disease (spongiform enceer almost exclusively in the UK, the country with by far the highest incidence of BSE. Laboratory studies, including transmission experiments in mice, provide strong support for the hypothesis that nvCJD is caused by BSE.

Từ khóa


Tài liệu tham khảo

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Wiley

Tập 88 Số s433

28-32

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