The requirement for eukaryotic initiation factor 4A (eIF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure

RNA - Tập 7 Số 3 - Trang 382-394 - 2001
Yuri V. Svitkin1, Arnim Pause1,2, Ashkan Haghighat1,3, Stéphane Pyronnet1, Gary W. Witherell4, Graham J. Belsham5, Nahum Sonenberg1
1Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, H3G 1Y6 Canada
2Present address: Bio-Mega Research Division Boehringer Ingelheim Canada, Laval, Quebec H7S 2G5, Canada
3Present address: Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA
4Questcor Pharmaceuticals, Inc., Hayward, California 94545, USA
5BBSRC Institute for Animal Health, Pirbright, Woking, Surrey, GU24 ONF, United Kingdom

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