The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis*

Critical Care Medicine - Tập 39 Số 6 - Trang 1351-1358 - 2011
Michael S. Gough1, Mary Morgan2, Cynthia M. Mack2, Denise Darling2, Lauren M. Frasier2, Kathleen P. Doolin2, Michael J. Apostolakos2, Judith C. Stewart2, Brian Graves2, Erland Arning2, Teodoro Bottiglieri2, Robert A. Mooney2, Mark W. Frampton2, Anthony P. Pietropaoli2
1Division of Pulmonary and Critical Care Medicine, Department of Nursing, University of Rochester Medical Center, Rochester, NY, USA.
2Baylor Research Institute (EA, TB), Institute of Metabolic Diseases, Dallas, TX.; Dr. Bottiglieri received honoraria/speaking fees and a grant from PamLab. Dr. Bottiglieri also holds stock options with MSI. The remaining authors have not disclosed any potential conflicts of interest.; For information regarding this article, E-mail: [email protected]; From the Division of Pulmonary and Critical Care Medicine (MSG, MAMM, CMM, LMF, MJA, JCS, MWF, APP), Department of Nursing (CMM, KPD, BTG), Department of Respiratory Care (DCD), Department of Environmental Medicine (MWF), and Department of Pathology and Laboratory Medicine (RAM), University of Rochester Medical Center, Rochester, NY; Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.ccmjournal.com).; Supported, in part, by NIH K23 HL080077, NCRR 1 UL1 RR024160-01, and T32 HL066988 grants.

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Critical Care Medicine

Tập 39 Số 6

1351-1358

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