The pineal volume: a three‐dimensional volumetric study in healthy young adults using 3.0 T MR data

International Journal of Developmental Neuroscience - Tập 27 - Trang 655-660 - 2009
Bo Sun1, Dan Wang2, Yuchun Tang1, Lingzhong Fan1, Xiangtao Lin1, Taifei Yu3, Hengtao Qi3, Zhenping Li1, Shuwei Liu1
1Research Center for Sectional and Imaging Anatomy, Shandong University School of Medicine, 44 Wenhua Xi Road, Jinan 250012, Shandong, China
2Institute of Experimental Nuclear Medicine, Shandong University School of Medicine, Jinan 250012, China
3Department of MR, Shandong Medical Imaging Research Institute, Jinan 250012, China

Tóm tắt

AbstractIt is usually difficult to distinguish small pineal tumors via routine or enhanced magnetic resonance (MR) scan. The knowledge of normal pineal size is helpful to detect small pineal lesions, while very few true volumetric data of pineal glands have been reported. Therefore, we obtained the accurate reference range of normal pineal volumes in 112 individuals aged 20–30 years recruited randomly from a healthy community sample. Transverse and sagittal 3.0 T magnetic resonance data were obtained using three‐dimensional (3D) T1‐weighted FSPGR and T2‐weighted SE sequences. True pineal volumes were measured from T1‐weighted images, while estimated volumes were calculated using pineal length, width and height. All the glands were divided into three types according to the maximum inner diameter of pineal cysts. The prevalence of asymptomatic pineal cyst is 25.00%, with a slight female predominance. In the whole sample, we found no gender differences of pineal volume, but a significant gender difference of pineal volume index. A significant correlation between pineal volume and asymptomatic cyst was found. After excluding cases with big pineal cysts, there were significant correlations between pineal volume and head circumference, body height and body weight, respectively. This study suggests that asymptomatic pineal cysts may exert an important influence on pineal volume.

Tài liệu tham khảo

Abramoff M.D., 2004, Image processing with image, J. Biophotonics Int., 11, 36 Amunts K., 2001, Advances in cytoarchitectonic mapping of the human cerebral cortex, Neuroimaging Clin. N. Am., 11, 151 10.1016/S0304-3940(02)00617-1 10.1177/000992289603500510 10.1007/s003810050175 10.1136/jnnp.56.2.207 Dougherty R.P., 2002, Measure Stack 10.3171/jns.1988.68.5.0689 Fleege M.A., 1994, Benign glial cysts of the pineal gland: unusual imaging characteristics with histologic correlation, Am. J. Neuroradiol., 15, 161 Golan J., 2002, Morphometric parameters of the human pineal gland in relation to age, body weight and height, Folia Morphol. (Warsz.), 61, 111 10.1007/BF00602604 10.1016/0006-8993(87)90720-7 10.1148/radiology.179.1.1848714 10.1111/j.1600-079X.1995.tb00172.x 10.1111/j.1749-6632.1994.tb56818.x 10.1023/A:1012773727022 10.1097/00004728-198707000-00005 10.1016/0024-3205(87)90272-4 Little K.M., 2001, Surgical approaches to pineal region tumors, J. Neurooncol., 54, 287, 10.1023/A:1012766902431 10.1016/0149-936X(87)90087-7 10.1016/S0031-3955(03)00206-2 Mamourian A.C., 1991, Enhancement of pineal cysts on MR images, Am. J. Neuroradiol., 12, 773 10.1634/theoncologist.2000-0312 10.1051/rnd:19880310 10.3174/ajnr.A0656 Rajarethinam R., 1995, Volume of the pineal gland in schizophrenia; an MRI study, Schizophr. Res., 14, 253, 10.1016/0920-9964(94)00077-L Reyes P.F., 1982, Age related histologic changes in the human pineal gland, Prog. Clin. Biol. Res., 92, 253 10.1002/1097-0142(196708)20:8<1203::AID-CNCR2820200804>3.0.CO;2-2 10.1155/2000/421719 10.1210/jc.80.4.1221 10.1007/BF02011087 Sumida M., 1996, Development of the pineal gland: measurement with MR, Am. J. Neuroradiol., 17, 233 Sun B., 2008, The pineal region: thin sectional anatomy with MR correlation in the coronal plane, Surg. Radiol. Anat., 30, 575, 10.1007/s00276-008-0375-9 10.1016/S0079-6123(08)62955-6 10.1002/path.1711080207 10.2214/ajr.155.1.2162137 10.1023/A:1012790213818 10.1227/00006123-198103000-00006 10.1097/00004728-199101000-00007 10.1016/S0924-977X(02)00108-6
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International Journal of Developmental Neuroscience

Tập 27

655-660

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