The impact of sexual dysfunction on health-related quality of life in people with multiple sclerosis

Multiple Sclerosis Journal - Tập 20 Số 5 - Trang 610-616 - 2014
Laura C. Schairer1, Frederick W. Foley2,3, Vance Zemon2, Tuula Tyry4, Denise I. Campagnolo4, Ruth Ann Marrie5, Elizabeth S. Gromisch2, David Schairer6
1Ferkauf Graduate School of Psychology, Yeshiva University, USA
2#N# 1Ferkauf Graduate School of Psychology, Yeshiva University, USA
3#N# 2Holy Name Medical Center, Multiple Sclerosis Center, USA
43Barrow Neurological Institute, USA
5#N# 4Departments of Internal Medicine and Community Health Sciences, University of Manitoba, Canada
6#N# 5Albert Einstein College of Medicine, Yeshiva University, USA

Tóm tắt

Background: Sexual dysfunction is a prevalent symptom in multiple sclerosis (MS) that may affect patients’ health-related quality of life (HrQoL). Objective: The objective of this paper is to examine the impact of sexual dysfunction on HrQoL in a large national sample using The Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19). Methods: Participants were recruited from a large MS registry, the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry. Participants self-reported demographic information and completed the Patient Determined Disease Steps (PDDS), MSISQ-19, and the Short Form-12 (SF-12). Results: The study population included 6183 persons (mean age: 50.6, SD = 9.6; 74.7% female, 42.3% currently employed). Using multivariate hierarchical regression analyses, all variables excluding gender predicted both the physical component summary (PCS-12) and the mental component summary (MCS-12) of the SF-12. Scores on the MSISQ-19 uniquely accounted for 3% of the variance in PCS-12 scores while disability level, as measured by PDDS, accounted for 31% of the variance. Conversely, MSISQ-19 scores uniquely accounted for 13% of the variance in MCS-12 scores, whereas disability level accounted for less than 1% of the variance. Conclusion: In patients with MS, sexual dysfunction has a much larger detrimental impact on the mental health aspects of HrQoL than severity of physical disability.

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Thông tin xuất bản

Multiple Sclerosis Journal

Tập 20 Số 5

610-616

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