The global prevalence of dementia: A systematic review and metaanalysis

Alzheimer's & Dementia - Tập 9 Số 1 - Trang 63 - 2013
Martin Prince1, Renata Bryce1, Emiliano Albanese1,2, Anders Wimo3,4, Wagner Silva Ribeiro5,1, Cleusa P. Ferri5,1
1Institute of Psychiatry, King's College London, London, UK
2Laboratory of Epidemiology, Demography, and Biometry, National Institute of Aging National Institutes of Health, Bethesda, Maryland, USA
3Aging Research Center, Karolinska Institutet, Stockholm, Sweden
4KI–Alzheimer Disease Research Centre, Karolinska Institutet Stockholm Sweden
5Department of Psychiatry, Federal University of Sao Paulo, Sao Paulo, Brazil

Tóm tắt

BackgroundThe evidence base on the prevalence of dementia is expanding rapidly, particularly in countries with low and middle incomes. A reappraisal of global prevalence and numbers is due, given the significant implications for social and public policy and planning.MethodsIn this study we provide a systematic review of the global literature on the prevalence of dementia (1980–2009) and metaanalysis to estimate the prevalence and numbers of those affected, aged ≥60 years in 21 Global Burden of Disease regions.ResultsAge‐standardized prevalence for those aged ≥60 years varied in a narrow band, 5%–7% in most world regions, with a higher prevalence in Latin America (8.5%), and a distinctively lower prevalence in the four sub‐Saharan African regions (2%–4%). It was estimated that 35.6 million people lived with dementia worldwide in 2010, with numbers expected to almost double every 20 years, to 65.7 million in 2030 and 115.4 million in 2050. In 2010, 58% of all people with dementia lived in countries with low or middle incomes, with this proportion anticipated to rise to 63% in 2030 and 71% in 2050.ConclusionThe detailed estimates in this study constitute the best current basis for policymaking, planning, and allocation of health and welfare resources in dementia care. The age‐specific prevalence of dementia varies little between world regions, and may converge further. Future projections of numbers of people with dementia may be modified substantially by preventive interventions (lowering incidence), improvements in treatment and care (prolonging survival), and disease‐modifying interventions (preventing or slowing progression). All countries need to commission nationally representative surveys that are repeated regularly to monitor trends.

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Alzheimer's & Dementia

Tập 9 Số 1

63

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