The global burden of anxiety disorders in 2010

Psychological Medicine - Tập 44 Số 11 - Trang 2363-2374 - 2014
Amanda J Baxter1,2, Theo Vos3, Kate M. Scott4, Alize J Ferrari1,2, Harvey Whiteford1,2
1Queensland Centre for Mental Health Research, Wacol, Australia
2School of Population Health, University of Queensland, Herston, Australia
3University of Washington, Institute for Health Metrics and Evaluation, Seattle, WA, USA
4Department of Psychological Medicine, University of Otago, Dunedin, New Zealand

Tóm tắt

BackgroundDespite their high prevalence, the global burden of anxiety disorders has never been calculated comprehensively. The new Global Burden of Disease (GBD) study has estimated burden due to morbidity and mortality caused by any anxiety disorder.MethodPrevalence was estimated using Bayesian meta-regression informed by data identified in a systematic review. Years of life lived with disability (YLDs) were calculated by multiplying prevalent cases by an average disability weight based on severity proportions (mild, moderate and severe). Disability-adjusted life years (DALYs) were then calculated and age standardized using global standard population figures. Estimates were also made for additional suicide mortality attributable to anxiety disorders. Findings are presented for YLDs, DALYs and attributable burden due to suicide for 21 world regions in 1990 and 2010.ResultsAnxiety disorders were the sixth leading cause of disability, in terms of YLDs, in both high-income (HI) and low- and middle-income (LMI) countries. Globally, anxiety disorders accounted for 390 DALYs per 100 000 persons [95% uncertainty interval (UI) 191–371 DALYs per 100 000] in 2010, with no discernible change observed over time. Females accounted for about 65% of the DALYs caused by anxiety disorders, with the highest burden in both males and females experienced by those aged between 15 and 34 years. Although there was regional variation in prevalence, the overlap between uncertainty estimates means that substantive differences in burden between populations could not be identified.ConclusionsAnxiety disorders are chronic, disabling conditions that are distributed across the globe. Future estimates of burden could be further improved by obtaining more representative data on severity state proportions.

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Tài liệu tham khảo

Ayuso-Mateos, 2006, Global Burden of Post-Traumatic Stress Disorder in the Year 2000: Version 1 Estimates. GBD 2000 Working Paper

10.1016/j.socscimed.2010.11.008

10.1007/s11920-011-0199-x

Andrews, 2000, Why does the burden of disease persist? Relating the burden of anxiety and depression to effectiveness of treatment, Bulletin of the World Health Organization, 78, 446

10.1001/archgenpsychiatry.2010.180

10.1017/S0033291709991036

Flaxman, 2013, An Integrative Metaregression Framework for Descriptive Epidemiology

10.1016/S0140-6736(12)61680-8

10.1016/S0140-6736(12)61729-2

Murray, 1996, The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020

10.1159/000073451

10.1017/S003329170300881X

Kessler, 2002, Neuropsychopharmacology: The Fifth Generation of Progress, 981

1997, National Survey of Mental Health and Wellbeing, 1997 (SMHWB)

2001–2002, National Epidemiologic Survey on Alcohol and Related Conditions Wave 1 and Wave 2

10.1016/S0140-6736(12)61899-6

10.1176/appi.ajp.157.5.669

10.1002/da.22230

Demyttenaere, 2004, Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys, Journal of the American Medical Association, 291, 2581, 10.1001/jama.291.21.2581

10.1002/da.10106

10.1017/S1121189X00001421

Kessler, 2007, Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization's World Mental Health Survey Initiative, World Psychiatry, 6, 168

10.1016/S0140-6736(13)61611-6

2008, The Global Burden of Disease: 2004 Update

2009, United States Medical Expenditure Panel Survey (MEPS) 2000–2009

10.1192/bjp.bp.107.039107

2013, Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)

10.1097/YCO.0b013e3283477a09

10.1371/journal.pmed.1000097

2000, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)

10.1016/S0140-6736(12)61766-8

Andrews, 2007, Tolkien II: A Needs-based, Costed Stepped-care Model for Mental Health Services

10.1176/appi.ps.53.1.80

10.1016/S0140-6736(13)61384-7

1993, The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research

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Psychological Medicine

Tập 44 Số 11

2363-2374

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