The central role of the antigen-specific receptor complex in triggering cytolytic activity of cytotoxic T lymphocytes

Chang TW, Celis E, Eisen HN & Solomon F (1979) Crawling movements of lymphocytes of lymphocytes on and beneath fibroblasts in culture. Proc. Natl. Acad. Sci. U.S.A.76, 2917?2921.

Brunner, KT, Nordin AA & Cerottini JC (1971) In vitro studies of sensitized lymphocytes and alloantibody-forming cells in mouse allograft immunity. In:Cellular Interactions in the Immune Response (Cohen S, Cudkowicz G & McCluskey RT, eds), pp 220?230, S. Karger, Basel.

Weissman IL (1973) Tumor immunity in vivo: Evidence that immune destruction of tumor leaves ?bystander? cells intact. J. Natl. Cancer Inst.51, 443?448.

Lightbody JJ & Bach FH (1972) Specificity of destruction by lymphocytes activated in mixed leukocyte culture. Transplant. Proc.4, 307?310.

Allison JP, McIntyre BW & Bloch D (1982) Tumor specific antigen of murine T-lymphoma defined with monoclonal antibody. J. Immunol.129, 2293?2300.

Haskins K, Kubo R, White J, Pigeon M, Kappler J & Marrack P (1983) The major histocompatibility complex-restricted antigen receptor in T cells. I. Isolation with a monoclonal antibody. J. Exp. Med.157, 1149?1169.

Meuer SC, Fitzgerald KA, Hussey RE, Hodgdon JC, Schlossman SF & Reinherz EL (1983) Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex. J. Exp. Med.157, 705?719.

Kranz DM, Tonegawa S & Eisen HN (1984) Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A.81, 7922?7926.

Staerz UD, Kanagawa O & Bevan MJ (1985) Hybrid antibodies can target sites for attack by T cells. Nature314, 628?631.

Perez P, Hoffman RW, Shaw S, Bluestone JA & Segal DM (1985) Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody. Nature316, 354?356.

Liu MA, Kranz DM, Kurnick JT, Boyle LA, Levy R & Eisen HN (1985) Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A., in press.

Hubbard SC, Kranz DM, Longmore GD & Eisen HN. Differential glycosylation of the ? and ? subunits of T-cell receptor from a cloned murine cytotoxic T lymphocyte cell line. To be submitted.

Meuer SC, Acuto O, Hussey RE, Hodgdon JC, Fitzgerald KA, Schlossman SF & Reinherz EL (1983) Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor. Nature303, 808?810.

Meuer SC, Hodgdon JC, Hussey RE, Protentis JP, Schlossman SF & Reinherz EL (1983) Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones. J. Exp. Med.158, 988?993.

Borst J, Prendiville MA & Terhorst C (1982) Complexity of the human T lymphocyte-specific cell surface antigen T3. J. Immunol.128, 1560?1565.

Brenner MB, Trowbridge IS & Strominger JL (1985) Cross-linking of human T cell receptor proteins: association between the T cell idiotype ? subunit and the T3 glycoprotein heavy subunit. Cell40, 183?190.

Forman J & Moller G (1973) Generation of cytotoxic lymphocytes in mixed lymphocyte reactions. J. Exp. Med.137, 672?685.

Berke G (1983) Cytotoxic T lymphocytes?how do they function? Immunol. Rev.72, 5?42.

Sitkovsky MV, Pasternack MS & Eisen HN (1982) Inhibition of cytotoxic T lymphocyte activity by Con A. J. Immunol.129, 1372?1376.

Sitkovsky MV, Kranz DM & Eisen HN. Anti-receptor antibody blocks lectin-dependent T cell-mediated cytotoxicity. In preparation.

Lancki DW & Fitch FW (1984) Fed. Proc. Fed. Am. Soc. Exp. Biol.43, 1659 (Abstract).

Schmitt-Verhulst AM. Personal communication.

Hoffman RW, Bluestone JA, Leo O & Shaw S (1985) Lysis of anti-T3-bearing murine hybridoma cells by human allospecific cytotoxic T cell clones and inhibition of that lysis by anti-T3 and anti-LFA-1 antibodies. J. Immunol.135, 5?8.

Mentzer SJ, Barbosa JA & Burakoff SJ (1985) T3 monoclonal antibody activation of nonspecific cytolysis: A mechanism of CTL inhibition. J. Immunol.135, 34?38.

Kuppers RC & Henney CS (1976) Evidence for direct linkage between antigen recognition and lytic expression in effector T cells. J. Exp. Med.143, 684?689.

Sitkovsky MV, Pasternack MS, Lugo JP, Klein JR & Eisen HN (1984) Isolation and partial characterization of Con A receptors in clonal cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A.81, 1519?1523.

Henkart PA (1985) Mechanism of lymphocyte-mediated cytotoxicity. Ann. Rev. Immunol.3, 31?58.

Dennert G & Podack ER (1983) Cytolysis by H-2 specific T killer cells: assembly of tubular complexes on target membranes. J. Exp. Med.157, 1483?1495.

Oettgen HC, Terhorst C, Cantley LC & Rosoff PM (1985) Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx. Cell40, 583?590.

Pasternack MS and Eisen HN (1985) A novel serine esterase expressed by cytotoxic T lymphocytes. Nature314, 743?745.