The Role of YAP and TAZ in Angiogenesis and Vascular Mimicry

Hillen, 2007, Tumour vascularization: Sprouting angiogenesis and beyond, Cancer Metastasis Rev., 26, 489, 10.1007/s10555-007-9094-7

Djonov, 2003, Vascular remodeling by intussusceptive angiogenesis, Cell Tissue Res., 314, 107, 10.1007/s00441-003-0784-3

Lamalice, 2007, Endothelial cell migration during angiogenesis, Circ. Res., 100, 782, 10.1161/01.RES.0000259593.07661.1e

Caduff, 1986, Scanning electron microscope study of the developing microvasculature in the postnatal rat lung, Anat. Rec., 216, 154, 10.1002/ar.1092160207

Otrock, 2007, Understanding the biology of angiogenesis: Review of the most important molecular mechanisms, Blood Cellsmoleculesand Dis., 39, 212, 10.1016/j.bcmd.2007.04.001

Deveza, 2012, Therapeutic angiogenesis for treating cardiovascular diseases, Theranostics, 2, 801, 10.7150/thno.4419

Couffinhal, 2001, The mechanisms of angiogenesis. Medical and therapeutic applications, La Revue de Medecine Interne, 22, 1064, 10.1016/S0248-8663(01)00472-6

2011, Evolution of angiogenesis, Int. J. Dev. Biol., 55, 345, 10.1387/ijdb.103212rm

Breier, 2000, Angiogenesis in embryonic development—A review, Placenta, 21, S11, 10.1053/plac.1999.0525

Klagsbrun, 1996, Vascular endothelial growth factor and its receptors, Cytokine Growth Factor Rev., 3, 259, 10.1016/S1359-6101(96)00027-5

Chung, 2011, Developmental and pathological angiogenesis, Annu. Rev. Cell Dev. Biol., 27, 563, 10.1146/annurev-cellbio-092910-154002

Lobov, 2007, Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting, Proc. Natl. Acad. Sci. USA, 104, 3219, 10.1073/pnas.0611206104

Betz, 2016, Cell behaviors and dynamics during angiogenesis, Co. Biol., 143, 2249

Flanagan, 1998, The ephrins and Eph receptors in neural development, Annu. Rev. Neurosci., 21, 309, 10.1146/annurev.neuro.21.1.309

Creamer, 2002, Angiogenesis in psoriasis, Angiogenesis, 5, 231, 10.1023/A:1024515517623

Tuo, 2015, Wnt signaling in age-related macular degeneration: Human macular tissue and mouse model, J. Transl. Med., 13, 330, 10.1186/s12967-015-0683-x

Fallah, 2019, Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases, J. Cell. Physiol., 110, 775

Zetter, 1998, Angiogenesis and tumor metastasis, Annu. Rev. Med., 49, 407, 10.1146/annurev.med.49.1.407

Bergers, 2003, Tumorigenesis and the angiogenic switch, Nat. Rev. Cancer, 3, 401, 10.1038/nrc1093

Lawler, 2002, Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth, J. Cell. Mol. Med., 6, 1, 10.1111/j.1582-4934.2002.tb00307.x

Carmeliet, 2000, Angiogenesis in cancer and other diseases, Nature, 407, 249, 10.1038/35025220

Totaro, 2018, YAP/TAZ upstream signals and downstream responses, Nat. Cell Biol., 20, 888, 10.1038/s41556-018-0142-z

Moya, 2018, Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine, Nat. Rev. Mol. Cell Biol., 20, 211, 10.1038/s41580-018-0086-y

Barba, 2015, The Hippo transducers TAZ and YAP in breast cancer: Oncogenic activities and clinical implications, J. Exp. Clin. Cancer Res., 17, e14

Hansen, 2015, YAP and TAZ: A nexus for Hippo signaling and beyond, Trends Cell Biol., 25, 499, 10.1016/j.tcb.2015.05.002

Zhang, 2015, YAP and TAZ take center stage in cancer, Biochemistry, 54, 6555, 10.1021/acs.biochem.5b01014

Csibi, 2012, Hippo-YAP and mTOR pathways collaborate to regulate organ size, Nat. Cell Biol., 14, 1244, 10.1038/ncb2634

Tumaneng, 2012, Organ size control by Hippo and TOR pathways, Curr. Biol., 22, R368, 10.1016/j.cub.2012.03.003

Hong, 2012, The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway, Semin. Cell Dev. Biol., 23, 785, 10.1016/j.semcdb.2012.05.004

Justice, 1995, The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation, Genes Dev., 9, 534, 10.1101/gad.9.5.534

Tapon, 2002, salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines, Cell, 110, 467, 10.1016/S0092-8674(02)00824-3

Wu, 2003, hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts, Cell, 114, 445, 10.1016/S0092-8674(03)00549-X

Lai, 2005, Control of cell proliferation and apoptosis by mob as tumor suppressor, mats, Cell, 120, 675, 10.1016/j.cell.2004.12.036

Pan, 2010, The hippo signaling pathway in development and cancer, Dev. Cell, 19, 491, 10.1016/j.devcel.2010.09.011

Saucedo, 2007, Filling out the Hippo pathway, Nat. Rev. Mol. Cell Biol., 8, 613, 10.1038/nrm2221

Zhao, 2007, Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control, Genes Dev., 21, 2747, 10.1101/gad.1602907

Callus, 2006, Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation, Febs J., 273, 4264, 10.1111/j.1742-4658.2006.05427.x

Praskova, 2008, MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation, Curr. Biol., 18, 311, 10.1016/j.cub.2008.02.006

Chan, 2005, The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1, Oncogene, 24, 2076, 10.1038/sj.onc.1208445

Yu, 2013, The Hippo pathway: Regulators and regulations, Genes Dev., 27, 355, 10.1101/gad.210773.112

Hao, 2008, Tumor suppressor LATS1 is a negative regulator of oncogene YAP, J. Biol. Chem., 283, 5496, 10.1074/jbc.M709037200

Piccolo, 2014, The biology of YAP/TAZ: Hippo signaling and beyond, Physiol. Rev., 94, 1287, 10.1152/physrev.00005.2014

Panciera, 2017, Mechanobiology of YAP and TAZ in physiology and disease, Nat. Rev. Mol. Cell Biol., 18, 758, 10.1038/nrm.2017.87

Zhao, 2011, Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein, Genes Dev., 25, 51, 10.1101/gad.2000111

Yang, 2015, Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules, Proc. Natl. Acad. Sci. USA, 112, 1785, 10.1073/pnas.1420850112

Yu, 2012, Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling, Cell, 150, 780, 10.1016/j.cell.2012.06.037

Gschwind, 2004, The discovery of receptor tyrosine kinases: Targets for cancer therapy, Nat. Rev. Cancer, 4, 361, 10.1038/nrc1360

Lai, 2018, TAZ enhances mammary cell proliferation in 3D culture through transcriptional regulation of IRS1, Cell. Signal., 52, 12, 10.1016/j.cellsig.2018.08.012

Fan, 2013, Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1, Proc. Natl. Acad. Sci. USA, 110, 2569, 10.1073/pnas.1216462110

Zhao, 2018, PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways, Mol. Cancer Res., 16, 1046, 10.1158/1541-7786.MCR-17-0593

Glienke, 2000, Differential gene expression by endothelial cells in distinct angiogenic states, Eur. J. Biochem., 267, 2820, 10.1046/j.1432-1327.2000.01325.x

Auerbach, 2003, Angiogenesis assays: A critical overview, Clin. Chem., 49, 32, 10.1373/49.1.32

Auerbach, 2000, Angiogenesis assays: Problems and pitfalls, Cancer Metastasis Rev., 19, 167, 10.1023/A:1026574416001

Staton, C.A., Lewis, C., and Bicknell, R. (2007). Angiogenesis Assays: A Critical Appraisal of Current Techniques, John Wiley & Sons.

Goodwin, 2007, In vitro assays of angiogenesis for assessment of angiogenic and anti-angiogenic agents, Microvasc. Res., 74, 172, 10.1016/j.mvr.2007.05.006

Cui, 2018, Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis, Biomaterials, 161, 164, 10.1016/j.biomaterials.2018.01.053

Song, 2018, Vascular Differentiation from Pluripotent Stem Cells in 3-D Auxetic Scaffolds, J. Tissue Eng. Regen. Med., 12, 1679, 10.1002/term.2695

Aase, 2007, Angiomotin regulates endothelial cell migration during embryonic angiogenesis, Genes Dev., 21, 2055, 10.1101/gad.432007

Zheng, 2009, Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis, Circ. Res., 105, 260, 10.1161/CIRCRESAHA.109.195156

Skouloudaki, K., and Walz, G. (2012). YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation. PLoS ONE, 7.

Dai, 2013, Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis, J. Biol. Chem., 288, 34041, 10.1074/jbc.M113.518019

Hong, 2017, Low angiomotin-p130 with concomitant high Yes-associated protein 1 expression is associated with adverse prognosis of advanced gastric cancer, Apmis, 125, 996, 10.1111/apm.12750

Singleton, 2007, CD44 Regulates Hepatocyte Growth Factor-mediated Vascular Integrity: ROLE OF c-Met, Tiam1/Rac1, DYNAMIN 2, AND CORTACTIN, J. Biol. Chem., 282, 30643, 10.1074/jbc.M702573200

Savani, 2001, Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis, J. Biol. Chem., 276, 36770, 10.1074/jbc.M102273200

Flynn, 2013, CD44 regulates vascular endothelial barrier integrity via a PECAM-1 dependent mechanism, Angiogenesis, 16, 689, 10.1007/s10456-013-9346-9

Stamenkovic, 2010, Merlin, a “magic” linker between the extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival, Curr. Protein Pept. Sci., 11, 471, 10.2174/138920310791824011

Badouel, 2011, SnapShot: The hippo signaling pathway, Cell, 145, 484, 10.1016/j.cell.2011.04.009

Tsuneki, 2014, Adhesion molecule-mediated hippo pathway modulates hemangioendothelioma cell behavior, Mol. Cell. Biol., 34, 4485, 10.1128/MCB.00671-14

Tsuneki, 2014, CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression, J. Biol. Chem., 289, 5357, 10.1074/jbc.M113.529313

Xu, 2010, CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma, Cancer Res., 70, 2455, 10.1158/0008-5472.CAN-09-2505

Wada, 2011, Hippo pathway regulation by cell morphology and stress fibers, Development, 138, 3907, 10.1242/dev.070987

Dupont, 2011, Role of YAP/TAZ in mechanotransduction, Nature, 474, 179, 10.1038/nature10137

Nakajima, 2017, Flow-dependent endothelial YAP regulation contributes to vessel maintenance, Dev. Cell, 40, 523, 10.1016/j.devcel.2017.02.019

Gegenfurtner, 2018, Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing, J. Cell Sci., 131, 212886, 10.1242/jcs.212886

Dickson, 1995, Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice, Development, 121, 1845, 10.1242/dev.121.6.1845

Oshima, 1996, TGF-β receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis, Dev. Biol., 179, 297, 10.1006/dbio.1996.0259

Larsson, 2001, Abnormal angiogenesis but intact hematopoietic potential in TGF-β type I receptor-deficient mice, EMBO J., 20, 1663, 10.1093/emboj/20.7.1663

Pefani, 2016, TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation, Mol. Cell, 63, 156, 10.1016/j.molcel.2016.05.012

Ma, 2016, Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways, Nat. Commun., 7, 11123, 10.1038/ncomms11123

Young, K., Tweedie, E., Conley, B., Ames, J., FitzSimons, M., Brooks, P., Liaw, L., and Vary, C.P.H. (2015). BMP9 crosstalk with the hippo pathway regulates endothelial cell matricellular and chemokine responses. PLoS ONE, 10.

Singh, 2016, Investigation of TGFβ1-induced long noncoding RNAs in endothelial cells, Int. J. Vasc. Med., 2016, 2459687

Clevers, 2006, Wnt/β-Catenin Signaling in Development and Disease, Cell, 127, 469, 10.1016/j.cell.2006.10.018

Hot, 2017, FZD10-Gα13 signalling axis points to a role of FZD10 in CNS angiogenesis, Cell. Signal., 32, 93, 10.1016/j.cellsig.2017.01.023

Park, 2015, Alternative Wnt signaling activates YAP/TAZ, Cell, 162, 780, 10.1016/j.cell.2015.07.013

Min, 2011, The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells, J. Clin. Investig., 121, 1882, 10.1172/JCI42556

Podgrabinska, 2002, Molecular characterization of lymphatic endothelial cells, Proc. Natl. Acad. Sci. USA, 99, 16069, 10.1073/pnas.242401399

Reneman, 2006, Wall shear stress–an important determinant of endothelial cell function and structure–in the arterial system in vivo, J. Vasc. Res., 3, 251, 10.1159/000091648

Lee, 2017, Fluid shear stress activates YAP1 to promote cancer cell motility, Nat. Commun., 8, 14122, 10.1038/ncomms14122

Ivanov, 2013, Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells, Mol. Cell. Biol., 33, 3749, 10.1128/MCB.01387-12

Sabine, 2015, FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature, J. Clin. Investig., 125, 3861, 10.1172/JCI80454

Johnson, 2008, Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity, Genes Dev., 22, 3282, 10.1101/gad.1727208

Cho, 2019, YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis, Circ. Res., 124, 225, 10.1161/CIRCRESAHA.118.313707

Patan, 2004, Vasculogenesis and angiogenesis, Cancer Treat. Res., 117, 3, 10.1007/978-1-4419-8871-3_1

Boone, 2006, Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65, Mol. Cell. Biol., 26, 77, 10.1128/MCB.26.1.77-87.2006

Nagasawa-Masuda, A., and Terai, K. (2017). Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization. PLoS ONE, 12.

Brigstock, 2002, Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61), Angiogenesis, 5, 153, 10.1023/A:1023823803510

Chaqour, 2006, Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins, Fed. Eur. Biochem. Soc. J., 273, 3639

Jiang, 2004, Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer, Endocr. Relat. Cancer, 11, 781, 10.1677/erc.1.00825

Lai, 2011, Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF, Cancer Res., 71, 2728, 10.1158/0008-5472.CAN-10-2711

Neto, 2018, YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development, eLife, 7, e31037, 10.7554/eLife.31037

Choi, 2015, Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2, Nat. Commun., 6, 6943, 10.1038/ncomms7943

Sakabe, 2017, YAP/TAZ-CDC42 signaling regulates vascular tip cell migration, Proc. Natl. Acad. Sci. USA, 114, 10918, 10.1073/pnas.1704030114

Olsson, 2006, VEGF receptor signalling? In control of vascular function, Nat. Rev. Mol. Cell Biol., 7, 359, 10.1038/nrm1911

Ferrara, 2003, The biology of VEGF and its receptors, Nat. Med., 9, 669, 10.1038/nm0603-669

Azad, T., Nouri, K., van Rensburg Janse, H.J., Hao, Y., and Yang, X. (2018). Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor. J. Vis. Exp., E58416.

Azad, 2018, A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis, Nat. Commun., 9, 1061, 10.1038/s41467-018-03278-w

Wang, 2017, YAP/TAZ orchestrate VEGF signaling during developmental angiogenesis, Dev. Cell, 42, 462, 10.1016/j.devcel.2017.08.002

He, 2018, Yes-associated protein promotes angiogenesis via signal transducer and activator of transcription 3 in endothelial cells, Circ. Res., 122, 591, 10.1161/CIRCRESAHA.117.311950

Bergers, 2005, The role of pericytes in blood-vessel formation and maintenance, Neuro Oncol., 7, 452, 10.1215/S1152851705000232

Paiva, 2018, Pericytes in the premetastatic niche, Cancer Res., 78, 2779, 10.1158/0008-5472.CAN-17-3883

Kato, 2018, Pulmonary pericytes regulate lung morphogenesis, Nat. Commun., 9, 2448, 10.1038/s41467-018-04913-2

Fazekas, 2001, Angiogenesis-dependent diseases and angiogenesis therapy, Pathol. Oncol. Res., 7, 85, 10.1007/BF03032573

Barreto, 2017, Identification of the mechanisms by which age alters the mechanosensitivity of mesenchymal stromal cells on substrates of differing stiffness: Implications for osteogenesis and angiogenesis, Acta Biomater., 53, 59, 10.1016/j.actbio.2017.02.031

Goetzl, 2017, Altered cargo proteins of human plasma endothelial cell–derived exosomes in atherosclerotic cerebrovascular disease, FASEB J., 31, 3689, 10.1096/fj.201700149

Lin, 2018, Yes-associated protein mediates angiotensin II-induced vascular smooth muscle cell phenotypic modulation and hypertensive vascular remodelling, Cell Prolif., 51, e12517, 10.1111/cpr.12517

Bharadwaj, 2013, Role of the retinal vascular endothelial cell in ocular disease, Prog. Retin. Eye Res., 32, 102, 10.1016/j.preteyeres.2012.08.004

Yan, 2018, Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation, Mol. Vis., 24, 83

Kim, 2017, YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation, J. Clin. Investig., 127, 3441, 10.1172/JCI93825

Zhu, 2018, YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells, Exp. Cell Res., 373, 155, 10.1016/j.yexcr.2018.10.007

Hao, G.-M., Lv, T.-T., Wu, Y., Wang, H.-L., Xing, W., Wang, Y., Li, C., Zhang, Z.-J., Wang, Z.-L., and Wang, W. (2017). The Hippo signaling pathway: A potential therapeutic target is reversed by a Chinese patent drug in rats with diabetic retinopathy. BMC Complementary Altern. Med., 17.

Um, 2017, Substance P accelerates wound healing in type 2 diabetic mice through endothelial progenitor cell mobilization and Yes-associated protein activation, Mol. Med. Rep., 15, 3035, 10.3892/mmr.2017.6344

Xu, 2018, Low-Intensity Pulsed Ultrasound Treatment Accelerates Angiogenesis by Activating YAP/TAZ in Human Umbilical Vein Endothelial Cells, Ultrasound Med. Biol., 44, 2655, 10.1016/j.ultrasmedbio.2018.07.007

Yuan, 2017, Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling, J. Biol. Chem., 292, 15002, 10.1074/jbc.M117.804005

Mammoto, 2018, YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α, Microvasc. Res., 119, 73, 10.1016/j.mvr.2018.04.003

Hanahan, 2011, Hallmarks of cancer: The next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013

Xu, 2019, TAZ Expression on Endothelial Cells Is Closely Related to Blood Vascular Density and VEGFR2 Expression in Astrocytomas, J. Neuropathol. Exp. Neurol., 78, 172, 10.1093/jnen/nly122

Venkataramani, 2018, CD31 expression determines redox status and chemoresistance in human angiosarcomas, Clin. Cancer Res., 24, 460, 10.1158/1078-0432.CCR-17-1778

Marti, 2015, YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors, Hepatology, 62, 1497, 10.1002/hep.27992

Pan, 2017, YAP signaling in gastric cancer-derived mesenchymal stem cells is critical for its promoting role in cancer progression, Int. J. Oncol., 51, 1055, 10.3892/ijo.2017.4101

Maniotis, 1999, Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry, Am. J. Pathol., 155, 739, 10.1016/S0002-9440(10)65173-5

Oliver, 2017, Vasculogenic mimicry signaling revisited: Focus on non-vascular VE-cadherin, Mol. Cancer, 16, 65, 10.1186/s12943-017-0631-x

Hendrix, 2016, Tumor cell vascular mimicry: Novel targeting opportunity in melanoma, Pharmacol. Ther., 159, 83, 10.1016/j.pharmthera.2016.01.006

Hendrix, 2003, Vasculogenic mimicry and tumour-cell plasticity: Lessons from melanoma, Nat. Rev. Cancer, 3, 411, 10.1038/nrc1092

Shirakawa, 2002, Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft, Cancer Res., 62, 560

Williamson, 2016, Vasculogenic mimicry in small cell lung cancer, Nat. Commun., 7, 13322, 10.1038/ncomms13322

Sood, 2001, Molecular determinants of ovarian cancer plasticity, Am. J. Pathol., 158, 1279, 10.1016/S0002-9440(10)64079-5

Cai, 2004, Tumor blood vessels formation in osteosarcoma: Vasculogenesis mimicry, Chin. Med. J., 117, 94

Li, 2010, Vasculogenic mimicry: A new prognostic sign of gastric adenocarcinoma, Pathol. Oncol. Res., 16, 259, 10.1007/s12253-009-9220-7

Streeter, 2002, Angiogenesis in bladder cancer—Prognostic marker and target for future therapy, Surg. Oncol., 11, 85, 10.1016/S0960-7404(02)00013-0

Sun, 2011, Promotion of tumor cell metastasis and vasculogenic mimicry by way of transcription coactivation by Bcl-2 and Twist1: A study of hepatocellular carcinoma, Hepatology, 54, 1690, 10.1002/hep.24543

Baeten, 2009, Prognostic role of vasculogenic mimicry in colorectal cancer, Dis. Colon Rectum, 52, 2028, 10.1007/DCR.0b013e3181beb4ff

Nguyen, 2015, YAP1 regulates OCT4 activity and SOX2 expression to facilitate self-renewal and vascular mimicry of stem-like cells, Stem Cells, 33, 1705, 10.1002/stem.1993

Wei, 2017, Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP-TEAD complex, Cancer Sci., 108, 478, 10.1111/cas.13138

Azad, 2018, The Hippo pathway component TAZ promotes immune evasion in human cancer through PD-L1, Cancer Res., 78, 1457, 10.1158/0008-5472.CAN-17-3139

Cross, 2001, FGF and VEGF function in angiogenesis: Signalling pathways, biological responses and therapeutic inhibition, Trends Pharmacol. Sci., 22, 201, 10.1016/S0165-6147(00)01676-X

Zhao, 2015, Targeting angiogenesis in cancer therapy: Moving beyond vascular endothelial growth factor, Oncologist, 20, 660, 10.1634/theoncologist.2014-0465