Giao thức REFER (REFer để thực hiện siêu âm tim): xác thực diến ra của một quy tắc quyết định lâm sàng, NT-proBNP, hoặc sự kết hợp của chúng, trong việc chẩn đoán suy tim ở tuyến chăm sóc ban đầu. Các lý do và thiết kế

BMC Cardiovascular Disorders - Tập 12 Số 1 - 2012
Lynda Tait1, Andrea Roalfe1, Jonathan Mant2, Martin R. Cowie3, Jonathan J Deeks4, Rachel Iles1, Pelham Barton5, Clare Taylor1, Marites Derit1, Richard Hobbs6
1Primary Care Clinical Sciences, Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
2General Practice & Primary Care Research Unit, University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 OSR, UK
3Imperial College London (Royal Brompton Hospital), London, SW3 6LY, UK
4Public Health, Epidemiology and Biostatistics, Public Health Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
5Health Economics Unit, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
6Department of General Practice, University of Oxford, 23-38 Hythe Bridge Street, Oxford, OX1 2ET, UK

Tóm tắt

Tóm tắt Giới thiệu Suy tim là nguyên nhân chính gây tử vong và bệnh tật. Do tỷ lệ tử vong cao, việc nhanh chóng xác định và điều trị những bệnh nhân đến gặp bác sĩ đa khoa với triệu chứng gợi ý suy tim là vô cùng quan trọng. Việc xác định bệnh nhân suy tim hoặc quyết định bệnh nhân nào cần được xét nghiệm thêm là một thách thức. Tất cả bệnh nhân nghi ngờ bị suy tim cần được chẩn đoán bằng các xét nghiệm khách quan như siêu âm tim, nhưng điều này thường tốn kém, trễ tràng và bị hạn chế do thiếu hụt nghiêm trọng các chuyên viên siêu âm được đào tạo. Hiện tại, các phương pháp chẩn đoán suy tim thay thế còn hạn chế. Các công cụ quyết định lâm sàng kết hợp các dấu hiệu lâm sàng, triệu chứng hoặc đặc điểm của bệnh nhân được thiết kế để hỗ trợ việc ra quyết định lâm sàng và được xác thực theo các quy trình phương pháp nghiêm ngặt. Nghiên cứu REFER nhằm xác định độ chính xác và hiệu quả chi phí của quy tắc quyết định lâm sàng đơn giản, mới và đã được phát triển trước đó của chúng tôi, một xét nghiệm peptide lợi niệu, hoặc sự kết hợp của chúng, trong việc phân loại bệnh nhân người lớn có triệu chứng trong thực hành tổng quát mà có triệu chứng gợi ý suy tim để chuyển gửi xét nghiệm siêu âm tim.

Từ khóa

#suy tim #quy tắc quyết định lâm sàng #NT-proBNP #siêu âm tim #nghiên cứu lâm sàng

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BMC Cardiovascular Disorders

Tập 12 Số 1

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