The International Collaboration on ADHD and Substance Abuse (ICASA): Mission, Results, and Future Activities

European Addiction Research - Tập 26 Số 4-5 - Trang 173-178 - 2020
Geurt van de Glind1,2, Christoffer Brynte3, Arvid Skutle4, Sharlene Kaye5, Maija Konstenius3, Frances R. Levin6, Frieda Mathys7, Zsolt Demetrovics8, Franz Moggi9, Josep Antoni Ramos‐Quiroga10,11,12,13, Arnt Schellekens14, Cleo L. Crunelle15, Geert Dom16, Wim van den Brink17, Johan Franck3
1Director ICASA Foundation, Radboud University Medical Hospital, Nijmegen, The Netherlands
2Teacher at Bachelor School of Nursing, Institute for Nursing Studies, University of Applied Science, Utrecht, The Netherlands
3Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
4Psykologkontoret, Bergen, Norway
5National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
6Division on Substance Use Disorders, New York State Psychiatric Institute, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY, USA
7Department of psychiatry University Hospital Brussels, Free University of Brussels, Brussels, Belgium
8Institute of Psychology, ELTE, Eötvös Loránd University, Budapest, Hungary
9Clinical Psychological Service, University Hospital of Psychiatry and Psychotherapy, Bern, Switzerland
10Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Spain
11Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
12Department of Psychiatry, Hospital Universitari Vall D’Hebron, Barcelona, Spain
13Psychiatric Genetics Unit, Vall d’Hebron Research Institute (VHIR), Barcelona, Spain
14Department of Psychiatry, Radboudumc, Donders Institute for Brain Cognition, and Behavior, Nijmegen, The Netherlands
15Department of Psychiatry, University Hospital Brussels (UZ Jette), Toxicological Center, University of Antwerp, Antwerp, Belgium
16Antwerp University & Hospital, Addiction Psychiatry, Psychiatric Center Alexian Brothers, Antwerp, Belgium
17Department of Psychiatry, Amsterdam University Medical Centers, Location Academic Medical Center (AMC), Amsterdam, The Netherlands

Tóm tắt

<b><i>Background:</i></b> The <i>International Collaboration on ADHD and Substance Abuse</i> (ICASA) is a network of 28 centers from 16 countries initiated to investigate the link between attention deficit-hyperactivity disorder (ADHD) and substance use disorder (SUD). In this article, we present the mission, the results of finished studies, and the current and future research projects of ICASA. Methods: During the past 10 years, 3 cross-sectional studies were conducted: two International ADHD in Substance use disorders Prevalence (IASP-1 and IASP-2) studies, directed at the screening, diagnosis, and the prevalence of adult ADHD in treatment-seeking patients with SUD, and the Continuous performance test for ADHD in SUD Patients (CASP) study, testing a novel continuous performance test in SUD patients with and without adult ADHD. Recently, the prospective International Naturalistic Cohort Study of ADHD and Substance Use Disorders (INCAS) was initiated, directed at treatment provision and treatment outcome in SUD patients with adult ADHD. <b><i>Results:</i></b> The IASP studies have shown that approximately 1 in 6 adult treatment-seeking SUD patients also have ADHD. In addition, those SUD patients with adult ADHD compared to SUD patients without ADHD report more childhood trauma exposure, slower infant development, greater problems controlling their temperament, and lower educational attainment. Comorbid patients also reported more risk-taking behavior, and a higher rate of other psychiatric disorders compared to SUD patients without ADHD. Screening, diagnosis, and treatment of this patient group are possible even before abstinence has been achieved. The results of the CASP study are reported separately in this special issue. <b><i>Conclusions:</i></b> The ICASA research to date has demonstrated a high prevalence of comorbid ADHD and SUD, associated with elevated rates of additional comorbidities and risk factors for adverse outcomes. More research is needed to find the best way to treat these patients, which is the main topic of the ongoing INCAS study.

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European Addiction Research

Tập 26 Số 4-5

173-178

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