The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity
Tóm tắt
Từ khóa
Tài liệu tham khảo
Schapira AH, Jenner P (2011) Etiology and pathogenesis of Parkinson’s disease. Mov Disord 26(6):1049–1055. doi: 10.1002/mds.23732
Xiong N, Long X, Xiong J, Jia M, Chen C, Huang J, Ghoorah D, Kong X et al (2012) Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson’s disease models. Crit Rev Toxicol 42(7):613–632. doi: 10.3109/10408444.2012.680431
Hang L, Thundyil J, Lim KL (2015) Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection. Ann N Y Acad Sci 1350:37–47. doi: 10.1111/nyas.12820
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT (2000) Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat Neurosci 3(12):1301–1306. doi: 10.1038/81834
Sai Y, Wu Q, Le W, Ye F, Li Y, Dong Z (2008) Rotenone-induced PC12 cell toxicity is caused by oxidative stress resulting from altered dopamine metabolism. Toxicol In Vitro 22(6):1461–1468. doi: 10.1016/j.tiv.2008.04.019
Arduino DM, Esteves AR, Cardoso SM (2011) Mitochondrial fusion/fission, transport and autophagy in Parkinson’s disease: when mitochondria get nasty. Park Dis 2011:767230. doi: 10.4061/2011/767230
Pacelli C, De Rasmo D, Signorile A, Grattagliano I, di Tullio G, D’Orazio A, Nico B, Comi GP et al (2011) Mitochondrial defect and PGC-1alpha dysfunction in parkin-associated familial Parkinson’s disease. Biochim Biophys Acta 1812(8):1041–1053. doi: 10.1016/j.bbadis.2010.12.022
Tsunemi T, La Spada AR (2012) PGC-1alpha at the intersection of bioenergetics regulation and neuron function: from Huntington’s disease to Parkinson’s disease and beyond. Prog Neurobiol 97(2):142–151. doi: 10.1016/j.pneurobio.2011.10.004
Kowald A, Kirkwood TB (2011) Evolution of the mitochondrial fusion-fission cycle and its role in aging. Proc Natl Acad Sci U S A 108(25):10237–10242. doi: 10.1073/pnas.1101604108
Youle RJ, van der Bliek AM (2012) Mitochondrial fission, fusion, and stress. Science 337(6098):1062–1065. doi: 10.1126/science.1219855
Santos D, Esteves AR, Silva DF, Januario C, Cardoso SM (2015) The impact of mitochondrial fusion and fission modulation in sporadic Parkinson’s disease. Mol Neurobiol 52(1):573–586. doi: 10.1007/s12035-014-8893-4
Martorell-Riera A, Segarra-Mondejar M, Munoz JP, Ginet V, Olloquequi J, Perez-Clausell J, Palacin M, Reina M et al (2014) Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death. EMBO J 33(20):2388–2407. doi: 10.15252/embj.201488327
Wu MT, Chou HN, Huang CJ (2014) Dietary fucoxanthin increases metabolic rate and upregulated mRNA expressions of the PGC-1alpha network, mitochondrial biogenesis and fusion genes in white adipose tissues of mice. Mar Drugs 12(2):964–982. doi: 10.3390/md12020964
Sai Y, Chen J, Ye F, Zhao Y, Zou Z, Cao J, Dong Z (2013) Dopamine release suppression dependent on an increase of intracellular Ca(2+) contributed to rotenone-induced neurotoxicity in PC12 cells. J Toxicol Pathol 26(2):149–157. doi: 10.1293/tox.26.149
Sai Y, Peng K, Ye F, Zhao X, Zhao Y, Zou Z, Cao J, Dong Z (2013) 14-3-3 Proteins in the regulation of rotenone-induced neurotoxicity might be via its isoform 14-3-3epsilon’s involvement in autophagy. Cell Mol Neurobiol 33(8):1109–1121. doi: 10.1007/s10571-013-9977-9
Peng K, Tao Y, Zhang J, Wang J, Ye F, Dan G, Zhao Y, Cai Y et al (2016) Resveratrol regulates mitochondrial biogenesis and fission/fusion to attenuate rotenone-induced neurotoxicity. Oxidative Med Cell Longev 2016:6705621. doi: 10.1155/2016/6705621
Knott AB, Bossy-Wetzel E (2008) Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration. Ann N Y Acad Sci 1147:283–292. doi: 10.1196/annals.1427.030
Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer’s disease. J Neurosci 29(28):9090–9103. doi: 10.1523/JNEUROSCI.1357-09.2009
Wang D, Wang J, Bonamy GM, Meeusen S, Brusch RG, Turk C, Yang P, Schultz PG (2012) A small molecule promotes mitochondrial fusion in mammalian cells. Angew Chem Int Ed Engl 51(37):9302–9305. doi: 10.1002/anie.201204589
Sharp WW, Fang YH, Han M, Zhang HJ, Hong Z, Banathy A, Morrow E, Ryan JJ et al (2014) Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J 28(1):316–326. doi: 10.1096/fj.12-226225
Labrousse AM, Zappaterra MD, Rube DA, van der Bliek AM (1999) C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol Cell 4(5):815–826
Smirnova E, Griparic L, Shurland DL, van der Bliek AM (2001) Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell 12(8):2245–2256
Zhang Y, Chan DC (2007) Structural basis for recruitment of mitochondrial fission complexes by Fis1. Proc Natl Acad Sci U S A 104(47):18526–18530. doi: 10.1073/pnas.0706441104
Ingerman E, Perkins EM, Marino M, Mears JA, McCaffery JM, Hinshaw JE, Nunnari J (2005) Dnm1 forms spirals that are structurally tailored to fit mitochondria. J Cell Biol 170(7):1021–1027. doi: 10.1083/jcb.200506078
Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160(2):189–200. doi: 10.1083/jcb.200211046
Ishihara N, Eura Y, Mihara K (2004) Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity. J Cell Sci 117(Pt 26):6535–6546. doi: 10.1242/jcs.01565
Hudson G, Amati-Bonneau P, Blakely EL, Stewart JD, He L, Schaefer AM, Griffiths PG, Ahlqvist K et al (2008) Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance. Brain 131(Pt 2):329–337. doi: 10.1093/brain/awm272
Huang S, Wang Y, Gan X, Fang D, Zhong C, Wu L, Hu G, Sosunov AA et al (2015) Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model. Diabetes 64(5):1728–1742. doi: 10.2337/db14-0758
Scarpulla RC (2012) Nucleus-encoded regulators of mitochondrial function: integration of respiratory chain expression, nutrient sensing and metabolic stress. Biochim Biophys Acta 1819(9-10):1088–1097. doi: 10.1016/j.bbagrm.2011.10.011
Haemmerle G, Moustafa T, Woelkart G, Buttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D et al (2011) ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat Med 17(9):1076–1085. doi: 10.1038/nm.2439
Li M, Vascotto C, Xu S, Dai N, Qing Y, Zhong Z, Tell G, Wang D (2012) Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1. Free Radic Biol Med 53(2):237–248. doi: 10.1016/j.freeradbiomed.2012.04.002
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troconso JC, Dawson VL et al (2011) PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson’s disease. Cell 144(5):689–702. doi: 10.1016/j.cell.2011.02.010
Ciron C, Lengacher S, Dusonchet J, Aebischer P, Schneider BL (2012) Sustained expression of PGC-1alpha in the rat nigrostriatal system selectively impairs dopaminergic function. Hum Mol Genet 21(8):1861–1876. doi: 10.1093/hmg/ddr618
Mudo G, Makela J, Di Liberto V, Tselykh TV, Olivieri M, Piepponen P, Eriksson O, Malkia A et al (2012) Transgenic expression and activation of PGC-1alpha protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease. Cell Mol Life Sci 69(7):1153–1165. doi: 10.1007/s00018-011-0850-z
Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K et al (2006) Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol 4(11):e369. doi: 10.1371/journal.pbio.0040369
Vaughan RA, Gannon NP, Barberena MA, Garcia-Smith R, Bisoffi M, Mermier CM, Conn CA, Trujillo KA (2014) Characterization of the metabolic effects of irisin on skeletal muscle in vitro. Diabetes Obes Metab 16(8):711–718. doi: 10.1111/dom.12268
Guo K, Lu J, Huang Y, Wu M, Zhang L, Yu H, Zhang M, Bao Y et al (2015) Protective role of PGC-1alpha in diabetic nephropathy is associated with the inhibition of ROS through mitochondrial dynamic remodeling. PLoS One 10(4):e0125176. doi: 10.1371/journal.pone.0125176
Cartoni R, Leger B, Hock MB, Praz M, Crettenand A, Pich S, Ziltener JL, Luthi F et al (2005) Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. J Physiol 567(Pt 1):349–358. doi: 10.1113/jphysiol.2005.092031
Sun M, Huang C, Wang C, Zheng J, Zhang P, Xu Y, Chen H, Shen W (2013) Ginsenoside Rg3 improves cardiac mitochondrial population quality: mimetic exercise training. Biochem Biophys Res Commun 441(1):169–174. doi: 10.1016/j.bbrc.2013.10.039
Valero T (2014) Mitochondrial biogenesis: pharmacological approaches. Curr Pharm Des 20(35):5507–5509
Palikaras K, Lionaki E, Tavernarakis N (2015) Coupling mitogenesis and mitophagy for longevity. Autophagy 11(8):1428–1430. doi: 10.1080/15548627.2015.1061172