The Curious World of Gonadal Development in Mammals

Blache, 2004, SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes, The Journal of Cell Biology, 166, 37, 10.1083/jcb.200311021 Burgoyne, 1988, Cell-autonomous action of the testis-determining gene: Sertoli cells are exclusively XY in XX-XY chimaeric mouse testes, Development, 102, 443, 10.1242/dev.102.2.443 Combes, 2009, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development, Developmental Dynamics, 238, 1033, 10.1002/dvdy.21925 Combes, 2009, Endothelial cell migration directs testis cord formation, Developmental Biology, 326, 112, 10.1016/j.ydbio.2008.10.040 Cool, 2011, Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning, Proceedings of the National Academy of Sciences of the United States of America, 108, 167, 10.1073/pnas.1010299108 Couse, 1999, Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta, Science (New York), 286, 2328, 10.1126/science.286.5448.2328 Garcia-Ortiz, 2009, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development, BMC Developmental Biology, 9, 36, 10.1186/1471-213X-9-36 Hernandez-Hernandez, 2009, Sox9 represses alpha-sarcoglycan gene expression in early myogenic differentiation, Journal of Molecular Biology, 394, 1, 10.1016/j.jmb.2009.08.057 Kashimada, 2010, Sry: The master switch in mammalian sex determination, Development, 137, 3921, 10.1242/dev.048983 Kim, 2006, Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination, PLoS Biology, 4, e187, 10.1371/journal.pbio.0040187 Koopman, 1991, Male development of chromosomally female mice transgenic for Sry, Nature, 351, 117, 10.1038/351117a0 Li, 2014, The sex-determining factors SRY and SOX9 regulate similar target genes and promote testis cord formation during testicular differentiation, Cell Reports, 8, 723, 10.1016/j.celrep.2014.06.055 Maatouk, 2008, Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal, Human Molecular Genetics, 17, 2949, 10.1093/hmg/ddn193 Minkina, 2014, DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation, Developmental Cell, 29, 511, 10.1016/j.devcel.2014.04.017 Palmer, 1991, In situ analysis of fetal, prepuberal and adult XX-XY chimaeric mouse testes: Sertoli cells are predominantly, but not exclusively, XY, Development, 112, 265, 10.1242/dev.112.1.265 Peacock, 2011, Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes, PloS One, 6, e26769, 10.1371/journal.pone.0026769 Polanco, 2007, Sry and the hesitant beginnings of male development, Developmental Biology, 302, 13, 10.1016/j.ydbio.2006.08.049 Sekido, 2008, Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer, Nature, 453, 930, 10.1038/nature06944 Svingen, 2013, Building the mammalian testis: Origins, differentiation, and assembly of the component cell populations, Genes & Development, 27, 2409, 10.1101/gad.228080.113 Tomizuka, 2008, R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling, Human Molecular Genetics, 17, 1278, 10.1093/hmg/ddn036 Uhlenhaut, 2009, Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation, Cell, 139, 1130, 10.1016/j.cell.2009.11.021 Vidal, 2001, Sox9 induces testis development in XX transgenic mice, Nature Genetics, 28, 216, 10.1038/90046 Wainwright, 2014, Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice, Developmental Biology, 395, 342, 10.1016/j.ydbio.2014.08.037 Wilhelm, 2005, Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination, Developmental Biology, 287, 111, 10.1016/j.ydbio.2005.08.039