The Circulating Inactive Form of Matrix Gla Protein Is a Surrogate Marker for Vascular Calcification in Chronic Kidney Disease

Parfrey, 1999, The clinical epidemiology of cardiac disease in chronic renal failure, J Am Soc Nephrol, 10, 1606, 10.1681/ASN.V1071606

London, 2003, Arterial media calcification in end-stage renal disease: Impact on all-cause and cardiovascular mortality, Nephrol Dial Transplant, 18, 1731, 10.1093/ndt/gfg414

Lehto, 1996, Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus, Arterioscler Thromb Vasc Biol, 16, 978, 10.1161/01.ATV.16.8.978

Schwarz, 2000, Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure, Nephrol Dial Transplant, 15, 218, 10.1093/ndt/15.2.218

Ibels, 1979, Arterial calcification and pathology in uremic patients undergoing dialysis, Am J Med, 66, 790, 10.1016/0002-9343(79)91118-5

Braun, 1996, Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients, Am J Kidney Dis, 27, 394, 10.1016/S0272-6386(96)90363-7

Goodman, 2000, Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis, N Engl J Med, 342, 1478, 10.1056/NEJM200005183422003

Moe, 2004, Natural history of vascular calcification in dialysis and transplant patients, Nephrol Dial Transplant, 19, 2387, 10.1093/ndt/gfh303

Yuen, 2006, The natural history of coronary calcification progression in a cohort of nocturnal haemodialysis patients, Nephrol Dial Transplant, 21, 1407, 10.1093/ndt/gfl021

Barreto, 2008, Phosphate binder impact on bone remodeling and coronary calcification–results from the BRiC study, Nephron Clin Pract, 110, 273, 10.1159/000170783

Price, 1983, Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone, Biochem Biophys Res Commun, 117, 765, 10.1016/0006-291X(83)91663-7

Munroe, 1999, Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome, Nat Genet, 21, 142, 10.1038/5102

Teebi, 1998, Keutel syndrome: Further characterization and review, Am J Med Genet, 78, 182, 10.1002/(SICI)1096-8628(19980630)78:2<182::AID-AJMG18>3.0.CO;2-J

Luo, 1997, Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein, Nature, 386, 78, 10.1038/386078a0

Shanahan, 2005, Mechanisms of vascular calcification in renal disease, Clin Nephrol, 63, 146, 10.5414/CNP63146

Zebboudj, 2002, Matrix GLA protein, a regulatory protein for bone morphogenetic protein-2, J Biol Chem, 277, 4388, 10.1074/jbc.M109683200

Murshed, 2004, Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins, J Cell Biol, 165, 625, 10.1083/jcb.200402046

Shearer, 1995, Vitamin K, Lancet, 345, 229, 10.1016/S0140-6736(95)90227-9

Schurgers, 2007, Post-translational modifications regulate matrix Gla protein function: Importance for inhibition of vascular smooth muscle cell calcification, J Thromb Haemost, 5, 2503, 10.1111/j.1538-7836.2007.02758.x

Hermans, 2007, Undercarboxylated matrix GLA protein levels are decreased in dialysis patients and related to parameters of calcium-phosphate metabolism and aortic augmentation index, Blood Purif, 25, 395, 10.1159/000108629

Cranenburg, 2008, The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification, J Vasc Res, 45, 427, 10.1159/000124863

Cranenburg, 2009, Uncarboxylated matrix Gla protein (ucMGP) is associated with coronary artery calcification in haemodialysis patients, Thromb Haemost, 101, 359, 10.1160/TH08-04-0241

Cockcroft, 1976, Prediction of creatinine clearance from serum creatinine, Nephron, 16, 31, 10.1159/000180580

Stevens, 2008, Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD, Am J Kidney Dis, 51, 395, 10.1053/j.ajkd.2007.11.018

Kauppila, 1997, New indices to classify location, severity and progression of calcific lesions in the abdominal aorta: A 25-year follow-up study, Atherosclerosis, 132, 245, 10.1016/S0021-9150(97)00106-8

Barreto, 2009, Vitamin D affects survival independently of vascular calcification in chronic kidney disease, Clin J Am Soc Nephrol, 4, 1128, 10.2215/CJN.00260109

Fitzmaurice, 2006, Confounding: Propensity score adjustment, Nutrition, 22, 1214, 10.1016/j.nut.2006.08.015

Shroff, 2008, The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis, Nephrol Dial Transplant, 23, 3263, 10.1093/ndt/gfn226

Schurgers, 2008, Matrix Gla-protein: The calcification inhibitor in need of vitamin K, Thromb Haemost, 100, 593, 10.1160/TH08-02-0087

Parker, 2009, Association of kidney function and uncarboxylated matrix Gla protein: Data from the Heart and Soul Study, Nephrol Dial Transplant, 24, 2095, 10.1093/ndt/gfp024

Schurgers, 2005, Novel conformation-specific antibodies against matrix gamma-carboxyglutamic acid (Gla) protein: Undercarboxylated matrix Gla protein as marker for vascular calcification, Arterioscler Thromb Vasc Biol, 25, 1629, 10.1161/01.ATV.0000173313.46222.43

Kohlmeier, 1995, Variation of phylloquinone (vitamin K1) concentrations in hemodialysis patients, Thromb Haemost, 74, 1252, 10.1055/s-0038-1649921

Pilkey, 2007, Subclinical vitamin K deficiency in hemodialysis patients, Am J Kidney Dis, 49, 432, 10.1053/j.ajkd.2006.11.041

Schurgers, 2004, Oral anticoagulant treatment: Friend or foe in cardiovascular disease?, Blood, 104, 3231, 10.1182/blood-2004-04-1277

Koos, 2005, Relation of oral anticoagulation to cardiac valvular and coronary calcium assessed by multislice spiral computed tomography, Am J Cardiol, 96, 747, 10.1016/j.amjcard.2005.05.014

Schurgers, 2007, Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats, Blood, 109, 2823, 10.1182/blood-2006-07-035345

Geleijnse, 2004, Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: The Rotterdam Study, J Nutr, 134, 3100, 10.1093/jn/134.11.3100

Beulens, 2009, High dietary menaquinone intake is associated with reduced coronary calcification, Atherosclerosis, 203, 489, 10.1016/j.atherosclerosis.2008.07.010