T cell activation and anti-tumor efficacy of anti-LAG-3 antibodies is independent of LAG-3 – MHCII blocking capacity

Journal for ImmunoTherapy of Cancer - Tập 3 Số S2 - 2015
Sašo Čemerski1, Shuxia Zhao1, Mélissa Chénard1, Jason Laskey1, Long Chen1, Rinkan Shukla1, Brian B. Haines1, Edward J. Hsieh1, Maribel Beaumont1, Jeanine D. Mattson1, Wendy M. Blumenschein1, Heather A. Hirsch1, Laurence Fayadat‐Dilman1, Linda Liang1, René de Waal Malefyt1
1Merck Research Laboratories

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