T Cell Receptor αβ Diversity Inversely Correlates with Pathogen-Specific Antibody Levels in Human Cytomegalovirus Infection

George Wang1,2, Pradyot Dash2, Jonathan A. McCullers3, Peter C. Doherty1, Paul G. Thomas1
1Department of Immunology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
2Division of Geriatric Medicine and Gerontology, Biology of Healthy Aging Program, Johns Hopkins University School of Medicine, 5505 Hopkins Bayview Circle, Baltimore, MD 21224, USA.
3Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA

Tóm tắt

CD8 + T cell diversity may be more important than T cell abundance in limiting the negative consequences of cytomegalovirus persistence.

Từ khóa


Tài liệu tham khảo

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