Synthesis and 13C‐NMR Spectroscopy of Methylated beta‐Cyclodextrins

Starch/Staerke - Tập 32 Số 5 - Trang 165-169 - 1980
J. Szejtli1, András Lipták2, Ildikó Jodál2, Péter Fügedi2, Péter P. Nánási2, András Neszmélyi3
1Chinoin Chemical and Pharmaceutical Works, Biochemical Laboratory, Endrödi Sándor u. 38 – 40, H-1026. Budapest
2Biochemical Institute of "Kossuth Lajos" University, Egyetem tér 1., H-4010 Debrecen
3Central Chemical Research Institute of Hungarian Academy of Sciences, Pusztaszeri út 57 – 69, H-1026 Budapest (Hungary)

Tóm tắt

AbstractThe methylated analogues of ß‐cyclodextrin dissolve in cold water 10 – 20 times better than ß‐cyclodextrin itself, however, quite unusually on heating they crystallize from the solution. The structure of heptakis‐(2,6‐di‐O‐methyl)‐ and heptakis‐(2,3,6‐tri‐O‐methyl)‐ß‐cyclodextrin was proved by gas‐liquid chromatographic and 1H‐NMR and 13C‐NMR spectroscopic investigations. The corresponding model compounds were synthetized and, according to 13C‐NMR spectroscopic investigations, a part of the so far published NMR assignations have to be corrected.

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Starch/Staerke

Tập 32 Số 5

165-169

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