Synthesis and in-vitro anticancer evaluation of bistacrine congeners
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alley, 1988, Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay, Cancer Res., 48, 589
Brana, 1997, Chromophore-modified bis-naphthalimides: synthesis and antitumor activity of bis-dibenz-[deh]isoquinoline-1,3-diones, J. Med. Chem., 40, 449, 10.1021/jm960295k
Canellakis, 1976, Diacridines: bifunctional intercalators. I. Chemistry, physical chemistry and growth inhibitory properties, Biochim. Biophys. Acta., 418, 277, 10.1016/0005-2787(76)90290-2
Chen, 1978, Diacridines, bifunctional intercalators. Chemistry and antitumor activity, J. Med. Chem., 21, 868, 10.1021/jm00207a006
Denny, 1989, DNA-intercalating agents as antitumour drugs: prospects for future design, Anticancer Drug Des., 4, 241
Diaz-Rubio, 1994, Phase I study of mitonafide with a 3-day administration schedule: early interruption due to severe central nervous system toxicity, Invest. New Drugs, 10, 25
Goldin, 1981, Current results of the screening program at the Division of Cancer Treatment, National Cancer Institute, Eur. J. Cancer, 17, 129, 10.1016/0014-2964(81)90027-X
Hu, 2000, A facile synthesis of bis-tacrine isosteres, Tetrahedron Lett., 41, 1815, 10.1016/S0040-4039(00)00036-8
McGeer, 1995, Alzheimer's disease: arthritis of the brain, Drug News Perspect., 8, 80
Roninson, 1992, The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo, Biochem. Pharmacol., 43, 95, 10.1016/0006-2952(92)90666-7
Sargent, 1946, The acridine series II. Dialkylaminoalkylamines from 9-chloro-1,2,3,4-tetrahydroacridine, J. Org. Chem., 11, 359, 10.1021/jo01174a009
Segal-Bendirjian, 1988, Selective loss of mitochondrial DNA after treatment of cells with ditercalinium (NSC 335153), an antitumor bis-intercalating agent, Cancer Res., 48, 4982
Skehan, 1990, New colorimetric cytotoxicity assay for anticancer drug screening, J. Natl Cancer Inst., 82, 1107, 10.1093/jnci/82.13.1107
Spicer, 2000, Bis(phenazine-1-carboxamides): structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs, J. Med. Chem., 43, 1350, 10.1021/jm990423f