Synthesis and Cytotoxicity of 1,6,8,9‐Substituted α‐Carboline Derivatives

Garcia M, 2007, Global Cancer Facts & Figures 2007, 2 10.1016/S0031-9422(98)00232-5 Carbriela MC, 1999, A β‐carboline alkaloid from the soft coral Lignopsis spongiosum, J Nat Prod, 62, 759, 10.1021/np980429s 10.1016/j.bbrc.2003.08.121 10.1006/exer.1996.0106 10.1093/jn/121.5.646 10.1016/j.bmc.2004.06.038 Ishida J, 1999, Antitumor agents 201. Cytotoxicity of harmine and β‐carboline analogs, Bioorg Med Chem Lett, 23, 3319, 10.1016/S0960-894X(99)00598-3 10.1016/S0960-894X(00)00679-X 10.1016/j.bmc.2008.07.002 10.1016/j.ejmech.2005.04.008 10.1021/np020592u 10.1016/S0040-4039(02)01023-7 10.1016/j.bmc.2007.05.033 Pawel NH, 1978, Cancerostatica II. Synthesis and preliminary cytostatic screening of some a‐carboline derivatives, Pol J Pharmacol Pharm, 30, 569 Lucia FM, 1987, Antineoplastic activity of azacarbazoles II. Effect of a‐carboline and its derivatives on transplantable animal neoplasms, Arch Immunol Ther Exp, 35, 221 Patricia VL, 2006, An improved synthesis of a‐carbolines under microwave irradiation, Org Lett, 8, 415, 10.1021/ol052552y Murtedza BM, 1980, Preparation of all the monochloro‐a‐carbolines and assignment of the 13, C n.m.r. spectrum of a‐carboline, J Chem Research (S), 43, 0577 Cédric S, 2007, Synthesis of 6‐substituted pyrido[2,3‐b]indoles by electrophilic substitution, Synlett, 14, 2237