Synthesis and Antimicrobial Evaluation of Sulfides, Sulfoxides, and Sulfones

Journal of the Korean Society for Applied Biological Chemistry - Tập 52 - Trang 34-39 - 2009
A. B. V. Kiran Kumar1, K. S. V. Krishna Rao2, M. Subhosh Chandra3, M. C. S. Subha1, Yong Lark Choi3
1Department of Chemistry, Sri Krishnadevaraya University, Anantapur, India
2Department of Chemistry, Yogi Vemana University, Kadapa, India
3Department of Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, Republic of Korea

Tóm tắt

Hydrogen peroxide, with sodium metavanadate as the catalyst, was used to achieve a highly efficient and selective oxidation of sulfides into sulfoxides and sulfones at room temperature in high yields and short reaction times. All of the sulfides oxidized into sulfoxides and sulfone derivatives were assayed for their in vitro antibacterial activities against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa, and antifungal activities against Aspergillus niger and Candida albicans. A remarkable inhibition of the growth of the bacterial and fungal strains was observed. This result suggested that the compounds are promising microbial agents.

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Thông tin xuất bản

Journal of the Korean Society for Applied Biological Chemistry

Tập 52

34-39

Thông tin tác giả