Synaptic structural plasticity: Role of synaptic shape

Synapse - Tập 3 Số 1 - Trang 1-11 - 1989
Etan J. Markus1, Ted L. Petit1
1Department of Psychology and Division of Life Sciences, University of Toronto, Scarborough, M1C 1A4, Canada

Tóm tắt

AbstractRecent research has indicated that synaptic curvature is an important and potentially critical plastic feature of the synapse. Alterations in synaptic shape are related to synaptic function, being found both during maturation and in adulthood following neuronal activation. In this paper we review the evidence supporting synaptic shape as a plastic feature of synaptic structure. We also propose several mechanisms which might underlie these changes in shape. Finally, we suggest the possible functional role of alterations in synaptic curvature, including its potential in altering synaptic transmission efficacy.

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