Symptomatic recovery and social functioning in major depression

Acta Psychiatrica Scandinavica - Tập 103 Số 4 - Trang 257-261 - 2001
Toshi A. Furukawa1, Hiroshi Takeuchi1, Takahiro Hiroe1, Hirobumi Mashiko2, K. Kamei3, Toshinori Kitamura4, Keiichi Takahashi4
1Department of Psychiatry, Nagoya City University Medical School, Nagoya, Japan
2Department of Neuropsychiatry, Fukushima Medical University School of Medicine, Fukushima, Japan
3Health Science Center for Students, Miyazaki University, Miyazaki, Japan and
4National Center for Neurology and Psychiatry, Tokyo and Chiba, Japan

Tóm tắt

Objective: To determine whether social functional recovery precedes, runs in parallel with, or lags behind symptomatic recovery from major depressive episodes. Method: Psychiatric out‐patients or in‐patients aged 18 years or over, diagnosed with unipolar major depressive disorder according to DSM‐IV, and who had received no antidepressant medication in the preceding 3 months were identified at 23 collaborating centres from all over Japan (n=95). They were rated with the 17‐item Hamilton Rating Scale for Depression (HRSD) and the Global Assessment Scale (GAS) monthly, and with the Social Adjustment Scale‐Self Report (SAS‐SR) 6‐monthly. Remission was defined as 7 or less on the HRSD and recovery as 2 or more consecutive months of remission. Results: The GAS ratings showed continuous amelioration from baseline to remission, remission to recovery, and after sustained recovery. The same trends were observed for SAS‐SR scores. Conclusion: We can expect further amelioration in social adjustment after symptomatic remission and recovery of major depressive episodes.

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