Mette Bertelsen1, Pia Jeppesen1, Lone Petersen1, Anne Thorup1, Johan ⊘hlenschlæger1, Phuong le Quach1, Torben Østergaard Christensen1, Gertrud Krarup1, Per J⊘rgensen2, Merete Nordentoft1
1Bispebjerg Hospital, Department of Psychiatry, Copenhagen, Denmark
2Sct. Hans Hospital, Roskilde, Denmark
Tóm tắt
BackgroundThose with first-episode psychosis are at high-risk of suicideAimsTo identify predictive factors for suicidal thoughts, plans and attempts,
and to investigate the rate of suicides and other deaths during the 5
years after first diagnosis and initiation of treatmentMethodA longitudinal, prospective, 5-year follow-up study of 547 individuals
with first-episode schizophrenia spectrum psychosis. Individuals
presenting for their first treatment in mental health services in two
circumscribed urban areas in Denmark were included in a randomised
controlled trial of integrated v. standard treatment.
All participants were followed in the Danish Cause of Death Register for
5 years. Suicidal behaviour and clinical and social status were assessed
using validated interviews and rating scales at entry, and at 1- and
2-year follow-upsResultsSixteen participants died during the follow-up. We found a strong
association between suicidal thoughts, plans and previous attempts,
depressive and psychotic symptoms and young age, and with suicidal plans
and attempts at 1- and 2-year follow-upConclusionsIn this first-episode cohort depressive and psychotic symptoms,
especially hallucinations, predicted suicidal plans and attempts, and
persistent suicidal behaviour and ideation were associated with high risk
of attempted suicide
