Structure of Linkage Disequilibrium in Plants

Annual Review of Plant Biology - Tập 54 Số 1 - Trang 357-374 - 2003
Sherry Flint‐Garcia1, Jeffry M. Thornsberry2, Edward S. Buckler2
1Department of Genetics, North Carolina State University, Raleigh, North Carolina, 27695, USA
2USDA-ARS, Plant Science Research Unit, Raleigh, North Carolina 27695; Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695;,

Tóm tắt

Future advances in plant genomics will make it possible to scan a genome for polymorphisms associated with qualitative and quantitative traits. Before this potential can be realized, we must understand the nature of linkage disequilibrium (LD) within a genome. LD, the nonrandom association of alleles at different loci, plays an integral role in association mapping, and determines the resolution of an association study. Recently, association mapping has been exploited to dissect quantitative trait loci (QTL). With the exception of maize and Arabidopsis, little research has been conducted on LD in plants. The mating system of the species (selfing versus outcrossing), and phenomena such as population structure and recombination hot spots, can strongly influence patterns of LD. The basic patterns of LD in plants will be better understood as more species are analyzed.

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Annual Review of Plant Biology

Tập 54 Số 1

357-374

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