Standardized remission criteria in schizophrenia

Acta Psychiatrica Scandinavica - Tập 113 Số 2 - Trang 91-95 - 2006
Jim van Os1, Tom Burns2, Roberto Cavallaro3, Stefan Leucht4, J. Peuskens5, Lars Helldin6, Miguel Bernardo7, Celso Arango8, W.W. Fleischhacker9, B. Lachaux10, John M. Kane11
1Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands and Institute of Psychiatry, UK
2University Of Oxford, Oxford, UK
3Department of Neuropsychiatric Sciences, San Raffaele Universitary Scientific Institute, Vita – Salute University Medical School, Milan, Italy
4Technische Universitat, Munchen, Germany#TAB#
5Catholic University Leuven, Belgium
6Trollhättan, Sweden
7Hospital Clinic, Barcelona, Spain
8Departamento de Psiquiatría, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
9Innsbruck University Clinic, Austria
10Centre Hospitalier Paul Guiraud, France
11The Zucker Hillside Hospital, New York, USA

Tóm tắt

Objective:  Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission.Method:  A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented.Results:  The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery.Conclusion:  The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.

Từ khóa


Tài liệu tham khảo

10.1126/science.1070532

Boydell J, 2001, The Comprehensive care of schizophrenia, 37

10.1176/appi.ajp.162.3.441

10.1001/archpsyc.1991.01810330075011

Ballenger JC, 1998, Consensus statement on panic disorder from the International Consensus Group on Depression and Anxiety, J Clin Psychiatry, 59, 47

Ballenger JC, 2001, Consensus statement on generalized anxiety disorder from the International Consensus Group on Depression and Anxiety, J Clin Psychiatry, 62, 53

Ballenger JC, 1998, Consensus statement on social anxiety disorder from the International Consensus Group on Depression and Anxiety, J Clin Psychiatry, 17, 54

Kane JM, 2003, Expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders. Introduction: methods, commentary, and summary, J Clin Psychiatry, 64, 5

Miller JR, 2000, Merritt's neurology, 778

10.1016/j.schres.2005.03.006

Van Os J, Validation of remission criteria for schizophrenia, Am J Psychiatry

National Institute for Clinical Excellence, 2002, Guidance on the use of newer (atypical) antipsychotic drugs for the treatment of schizophrenia

National Institute for Clinical Excellence, 2002, Schizophrenia: core interventions in the treatment and management of schizophrenia in primary and secondary care

Thông tin
Thông tin xuất bản

Acta Psychiatrica Scandinavica

Tập 113 Số 2

91-95

Thông tin tác giả