Spontaneous bowel perforation due to norovirus: a case report

Cases Journal - Tập 2 - Trang 1-3 - 2009
Nikhil Pawa1, Andrew P Vanezis1, Matthew G Tutton1
1Department of General Surgery, Colchester University Hospital, Colchester, UK

Tóm tắt

Norovirus is the leading cause of epidemic gastroenteritis worldwide but the disease is usually self-limiting and generally only causes serious health problems in the young, elderly and immunocompromised. The authors report a case of bowel perforation in an elderly Caucasian lady with confirmed infection with Norovirus genogroup II and no other presumptive cause. To the authors' knowledge this is the first such case of bowel perforation due to Norovirus. Viral gastroenteritis should be considered in the list of differentials when no obvious cause of bowel perforation can be identified to minimise morbidity and mortality.

Tài liệu tham khảo

Patel MM, Widdowson MA, Glass RI, et al: Systematic literature review of role of Noroviruses in sporadic gastroenteritis. Emerg Infect Dis. 2008, 14: 1224-31. 10.3201/eid1405.071426. Health Protection Agency FAQs. [http://www.hpa.org.uk] Dancer SJ: Norovirus: an established viral plague. J R Coll Physicians Edin. 2008, 38: 314-6. Investigation update on the Carnival Liberty: Centres for disease control and prevention. [http://www.cdc.gov] Lopman B, Zambon M, Brown DW: The evolution of Norovirus, the 'Gastric flu'. PLoS Med. 2008, 5: e42-10.1371/journal.pmed.0050042. doi:10.1371/journal.pmed.0050042 Health Protection Report- Norovirus Update 2007. [http://www.hpa.org.uk] Kaplan JE, Feldman R, Campbell DS, et al: The frequency of a Norwalk-like pattern of illness in outbreaks of acute gastroenteritis. Am J Public Health. 1982, 72: 1329-32. 10.2105/AJPH.72.12.1329. Lindesmith L, Moe C, Marionneau S, et al: Human susceptibility and resistance to Norwalk virus infection. Nat Med. 2003, 9: 548-53. 10.1038/nm860. Ozawa K, Oka T, Takeda N, et al: Norovirus Infections in Symptomatic and Asymptomatic Food Handlers in Japan. J Clin Microbiol. 2007, 45: 3996-4005. 10.1128/JCM.01516-07. Tu ET, Bull RA, Kim MJ, et al: Norovirus Excretion in an Aged-Care Setting. J Clin Microbiol. 2008, 46: 2119-21. 10.1128/JCM.02198-07.