Single nucleotide polymorphisms in CEL‐HYB1 increase risk for chronic pancreatitis through proteotoxic misfolding

10.1194/jlr.P041103

10.1016/j.pan.2016.10.006

Dalva M., 2020, Pathogenic carboxyl ester lipase (CEL) variants interact with the normal CEL protein in pancreatic cells, Cells, 9, 10.3390/cells9010244

10.1371/journal.pone.0115421

10.1371/journal.pone.0165567

10.1016/j.pan.2020.01.011

10.1038/ng.3249

10.1007/s10620-017-4601-3

10.1136/gutjnl-2018-315994

10.1194/jlr.R200013-JLR200

10.1074/jbc.RA118.001934

10.1016/j.pan.2017.12.001

10.1074/jbc.M111.222679

10.1038/nrdp.2017.60

Kumar B. V., 1992, Structure of the human pancreatic cholesterol esterase gene, Biochemistry, 31, 6077, 10.1021/bi00141a017

10.1001/jamapediatrics.2015.4955

10.14309/ajg.0000000000000051

10.1016/0888-7543(92)90134-E

10.1016/j.ajpath.2017.08.017

10.1007/s003359900762

10.1006/jmbi.2001.4979

10.1016/j.pan.2019.04.006

10.1038/ng1708

10.2337/db13-1012

10.1097/MOG.0000000000000380

10.1016/j.bbadis.2015.04.002

10.1074/jbc.M114.574244

Vesterhus M., 2010, Pancreatic function in carboxyl‐ester lipase knockout mice, Pancreatology, 10, 467, 10.1159/000266284

10.1097/MPA.0000000000000715

10.1074/jbc.M116.734384

Xiao X., 2017, A carboxyl ester lipase (CEL) mutant causes chronic pancreatitis by forming intracellular aggregates that activate apoptosis, Journal of Biological Chemistry, 292, 7744, 10.1074/jbc.A116.734384

10.1074/jbc.M111.249813

10.1038/ajg.2012.126

10.1053/j.gastro.2016.02.071