Simultaneous PET-MRI: a new approach for functional and morphological imaging

Cherry, S.R. In vivo molecular and genomic imaging: new challenges for imaging physics. Phys. Med. Biol. 49, R13–R48 (2004).

Marzola, P., Osculati, F. & Sbarbati, A. High field MRI in preclinical research. Eur. J. Radiol. 48, 165–170 (2003).

Townsend, D.W., Beyer, T. & Blodgett, T.M. PET/CT scanners: a hardware approach to image fusion. Semin. Nucl. Med. 33, 193–204 (2003).

Shao, Y. et al. Development of a PET detector system compatible with MRI/NMR systems. IEEE Trans. Nucl. Sci. 44, 1167–1171 (1997).

Yamamoto, S., Mazumoto, K. & Senda, M. Development of a multi-slice dual layer MR-compatible animal PET system using DOI detectors. J. Nucl. Med. 48 (Suppl.), 89P (2007).

Marsden, P.K., Strul, D., Keevil, S.F., Williams, S.C. & Cash, D. Simultaneous PET and NMR. Br. J. Radiol. 75 (Spec. No.), S53–S59 (2002).

Shao, Y. et al. Simultaneous PET and MR imaging. Phys. Med. Biol. 42, 1965–1970 (1997).

Raylman, R.R. et al. Simultaneous MRI and PET imaging of a rat brain. Phys. Med. Biol. 51, 6371–6379 (2006).

Raylman, R.R. et al. Simultaneous acquisition of magnetic resonance spectroscopy (MRS) data and positron emission tomography (PET) images with a prototype MR-compatible, small animal PET imager. J. Magn. Reson. 186, 305–310 (2007).

Garlick, P.B. et al. PET and NMR dual acquisition (PANDA): applications to isolated, perfused rat hearts. NMR Biomed. 10, 138–142 (1997).

Catana, C. et al. Simultaneous acquisition of multislice PET and MR Images: initial results with a MR-compatible PET scanner. J. Nucl. Med. 47, 1968–1976 (2006).

Lucas, A.J. et al. Development of a combined microPET-MR system. Technol. Cancer Res. Treat. 5, 337–341 (2006).

Gilbert, K.M., Handler, W.B., Scholl, T.J., Odegaard, J.W. & Chronik, B.A. Design of field-cycled magnetic resonance systems for small animal imaging. Phys. Med. Biol. 51, 2825–2841 (2006).

Judenhofer, M.S. et al. Simultaneous PET/MR images, acquired with a compact MRI compatible PET detector in a 7 Tesla magnet. Radiology 244, 807–814 (2007).

Schlyer, D. et al. First images from the BNL simultaneous PET/MRI scanner. J. Nucl. Med. 48 (Suppl.), 89P (2007).

Schlemmer, H.-P. et al. Simultaneous MR/PET for brain imaging: first patient scans. J. Nucl. Med. 48 (Suppl.), 45P (2007).

Pichler, B.J. et al. Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI. J. Nucl. Med. 47, 639–647 (2006).

Shields, A.F. et al. Imaging proliferation in vivo with [F-18]FLT and positron emission tomography. Nat. Med. 4, 1334–1336 (1998).

Ding, Y., Sugano, Y., Fowler, J. & Salata, C. Synthesis of the racemate and individual enantiomeres of [11C]methylphenidate for studying presynaptic dopaminergic neuron with positron emission tomography. J. Labelled Comp. Radiopharm. 34, 989–997 (1994).

Weber, R., Ramos-Cabrer, P., Wiedermann, D., van Camp, N. & Hoehn, M. A fully noninvasive and robust experimental protocol for longitudinal fMRI studies in the rat. Neuroimage 29, 1303–1310 (2006).

Friedman, L. & Glover, G.H. Report on a multicenter fMRI quality assurance protocol. J. Magn. Reson. Imaging 23, 827–839 (2006).

Pichler, B. et al. Studies with a prototype high resolution PET scanner based on LSO-APD modules. IEEE Trans. Nucl. Sci. 45, 1298–1302 (1998).

Tai, Y.C. et al. Performance evaluation of the microPET focus: a third-generation microPET scanner dedicated to animal imaging. J. Nucl. Med. 46, 455–463 (2005).

Slates, R.B. et al. A study of artefacts in simultaneous PET and MR imaging using a prototype MR compatible PET scanner. Phys. Med. Biol. 44, 2015–2027 (1999).

Tkac, I. et al. Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T. Magn. Reson. Med. 52, 478–484 (2004).

Montandon, M.L. & Zaidi, H. Atlas-guided non-uniform attenuation correction in cerebral 3D PET imaging. Neuroimage 25, 278–286 (2005).

Yang, Y. et al. Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging. Phys. Med. Biol. 49, 2527–2545 (2004).

Siegel, S. & Dahlbom, M. Implementation and evaluation of a calculated attenuation correction for PET. IEEE Trans. Nucl. Sci. 39, 1117–1121 (1992).

Tai, C. et al. Performance evaluation of the microPET P4: a PET system dedicated to animal imaging. Phys. Med. Biol. 46, 1845–1862 (2001).

Reischl, G. et al. Simplified, automated synthesis of 3′-[18F]fluoro-3′-deoxy-thymidine ([18F]FLT) and simple method for metabolic analysis in plasma. Radiochim. Acta 94, 447–451 (2006).