Các hạt nano bạc: Tổng hợp, đặc trưng, tính chất, ứng dụng và các phương pháp điều trị

International Journal of Molecular Sciences - Tập 17 Số 9 - Trang 1534
Xifeng Zhang1, Zhi Guo Liu2, Wei Shen3, Sangiliyandi Gurunathan4
1College of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan 430023, China. [email protected].
2College of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan 430023, China. [email protected].
3Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China. [email protected].
4Department of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea. [email protected].

Tóm tắt

Các tiến bộ gần đây trong lĩnh vực nanoscience và nanotechnology đã thay đổi một cách căn bản cách chúng ta chẩn đoán, điều trị và ngăn ngừa nhiều bệnh tật trong mọi khía cạnh của cuộc sống con người. Các hạt nano bạc (AgNPs) là một trong những loại vật liệu nano quan trọng và hấp dẫn nhất trong số các hạt nano kim loại liên quan đến ứng dụng y sinh. AgNPs đóng vai trò quan trọng trong nanoscience và nanotechnology, đặc biệt là trong nanomedicine. Mặc dù một số kim loại quý đã được sử dụng cho nhiều mục đích khác nhau, nhưng AgNPs lại được tập trung vào các ứng dụng tiềm năng trong chẩn đoán và điều trị ung thư. Trong bài tổng quan này, chúng tôi thảo luận về việc tổng hợp AgNPs bằng các phương pháp vật lý, hóa học và sinh học. Chúng tôi cũng thảo luận về các tính chất của AgNPs và các phương pháp để đặc trưng hóa chúng. Quan trọng hơn, chúng tôi thảo luận sâu rộng về các ứng dụng sinh học đa chức năng của AgNPs; ví dụ, như là các tác nhân kháng khuẩn, kháng nấm, kháng virus, kháng viêm, kháng tăng mạch, và kháng ung thư, cũng như cơ chế hoạt động của AgNPs trong điều trị ung thư. Ngoài ra, chúng tôi cũng thảo luận về các phương pháp điều trị và thách thức trong liệu pháp ung thư sử dụng AgNPs. Cuối cùng, chúng tôi kết luận bằng cách thảo luận về triển vọng tương lai của AgNPs.

Từ khóa


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