Shape memory alloy–based biopsy device for active locomotive intestinal capsule endoscope

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - Tập 229 Số 3 - Trang 255-263 - 2015
Viet Ha Le1, Hernando León-Rodríguez1, Cheong Lee1, Hyunchul Choi1, Zhen Jin1, Kim Tien Nguyen1, Gwangjun Go1, Seong-Young Ko1, Jong‐Oh Park1, Sukho Park1
1School of Mechanical Engineering, Chonnam National University, Gwangju, Korea

Tóm tắt

Recently, capsule endoscopes have been used for diagnosis in digestive organs. However, because a capsule endoscope does not have a locomotive function, its use has been limited to small tubular digestive organs, such as small intestine and esophagus. To address this problem, researchers have begun studying an active locomotive intestine capsule endoscope as a medical instrument for the whole gastrointestinal tract. We have developed a capsule endoscope with a small permanent magnet that is actuated by an electromagnetic actuation system, allowing active and flexible movement in the patient’s gut environment. In addition, researchers have noted the need for a biopsy function in capsule endoscope for the definitive diagnosis of digestive diseases. Therefore, this paper proposes a novel robotic biopsy device for active locomotive intestine capsule endoscope. The proposed biopsy device has a sharp blade connected with a shape memory alloy actuator. The biopsy device measuring 12mm in diameter and 3mm in length was integrated into our capsule endoscope prototype, where the device’s sharp blade was activated and exposed by the shape memory alloy actuator. Then the electromagnetic actuation system generated a specific motion of the capsule endoscope to extract the tissue sample from the intestines. The final biopsy sample tissue had a volume of about 6mm3, which is a sufficient amount for a histological analysis. Consequently, we proposed the working principle of the biopsy device and conducted an in-vitro biopsy test to verify the feasibility of the biopsy device integrated into the capsule endoscope prototype using the electro-magnetic actuation system.

Từ khóa


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Thông tin xuất bản

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Tập 229 Số 3

255-263

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