Sex difference in the association between pyrethroids exposure and sleep problems among adolescents: NHANES 2007–2014
Tóm tắt
Pyrethroids have been widely used in the United States and worldwide. Few studies examined the effect of pyrethroids exposure on sleep problems among adolescents. This study investigated the associations between pyrethroids exposure and sleep problems in male and female adolescents. The data were used from the National Health and Nutrition Examination Survey 2007–2014. In this study, 3-Phenoxybenzoic Acid (3-PBA) was used as a validated biomarker for pyrethroids exposure. The association between urinary 3-PBA and sleep problems was analyzed using logistic regression models. A total of 805 adolescents aged 16–20 years old were included in this study. The proportion of sleep problems was higher in females than in males (10.18% vs.7.35%, P = 0.154). A significant interaction was found between sex and 3-PBA (P interaction = 0.021) in the risk of sleep problems. A positive association of 3-PBA exposure with sleep problems was observed in male adolescents after adjusting for all the other covariates (OR = 4.04, 95% CI 1.31, 12.42). No statistically significant association was observed in female adolescents. A positive association was observed between pyrethroids exposure and sleep problems in male adolescents, but not in female adolescents. More studies are required to confirm our findings.
Tài liệu tham khảo
Baker SE et al (2004) Isotope dilution high-performance liquid chromatography-tandem mass spectrometry method for quantifying urinary metabolites of synthetic pyrethroid insecticides. Arch Environ Contam Toxicol 46:281–288. https://doi.org/10.1007/s00244-003-3044-3
Bao W et al (2020) Association between exposure to pyrethroid insecticides and risk of all-cause and cause-specific mortality in the general US adult population. JAMA Intern Med 180:367–374. https://doi.org/10.1001/jamainternmed.2019.6019
Barr DB et al (2010) Urinary concentrations of metabolites of pyrethroid insecticides in the general U.S. population: national health and nutrition examination survey 1999–2002. Environ Health Perspect 118:742–748. https://doi.org/10.1289/ehp.0901275
Benjafield AV et al (2019) Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med 7:687–698. https://doi.org/10.1016/s2213-2600(19)30198-5
Bhardwaj, K., et al. 2020. Pyrethroids: Natural Bioactive Products in Sustainable Agriculture. In: Joginder Singh, Ajar Nath Yadav (Eds). Natural Bioactive Products in Sustainable Agriculture. Singapore: Springer
Blunden S et al (2000) Behavior and neurocognitive performance in children aged 5–10 years who snore compared to controls. J Clin Exp Neuropsychol 22:554–568. https://doi.org/10.1076/1380-3395(200010)22:5;1-9;ft554
Boeniger MF et al (1993) Interpretation of urine results used to assess chemical exposure with emphasis on creatinine adjustments: a review. Am Ind Hyg Assoc J 54:615–627. https://doi.org/10.1080/15298669391355134
Bradberry SM et al (2005) Poisoning due to pyrethroids. Toxicol Rev 24:93–106. https://doi.org/10.2165/00139709-200524020-00003
Cappuccio FP, Miller MA (2017) Sleep and cardio-metabolic disease. Curr Cardiol Rep 19:110. https://doi.org/10.1007/s11886-017-0916-0
Chargui I et al (2010) Erythrocyte antioxidants enzymes imbalance following subcutaneous pyrethroid treatments in rats of different sex. Environ Toxicol Pharmacol 30:116–120. https://doi.org/10.1016/j.etap.2010.04.005
Darwiche W et al (2018) Impact of chronic exposure to the pesticide chlorpyrifos on respiratory parameters and sleep apnea in juvenile and adult rats. PLoS One 13:e0191237. https://doi.org/10.1371/journal.pone.0191237
Drake CL et al (2004) Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep 27:1453–1462. https://doi.org/10.1093/sleep/27.8.1453
Filip I et al (2017) Public health burden of sleep disorders: underreported problem. J Public Health 25:243–248. https://doi.org/10.1007/s10389-016-0781-0
Fuhrimann S et al (2022) Recent pesticide exposure affects sleep: a cross-sectional study among smallholder farmers in Uganda. Environ Int 158:106878. https://doi.org/10.1016/j.envint.2021.106878
Fund N et al (2020) The epidemiology of sleep disorders in Israel: results from a population-wide study. Sleep Med 67:120–127. https://doi.org/10.1016/j.sleep.2019.10.010
Grandner MA et al (2013) Sleep-related behaviors and beliefs associated with race/ethnicity in women. J Natl Med Assoc 105:4–15. https://doi.org/10.1016/s0027-9684(15)30080-8
Guo X et al (2023) Exploratory analysis of the association between pyrethroid exposure and rheumatoid arthritis among US adults: 2007–2014 data analysis from the national health and nutrition examination survey (NHANES). Environ Sci Pollut Res Int 30:14413–14423
Kim J et al (2014) Permethrin alters adipogenesis in 3T3-L1 adipocytes and causes insulin resistance in C2C12 myotubes. J Biochem Mol Toxicol 28:418–424. https://doi.org/10.1002/jbt.21580
Koren D, Taveras EM (2018) Association of sleep disturbances with obesity, insulin resistance and the metabolic syndrome. Metabolism 84:67–75. https://doi.org/10.1016/j.metabol.2018.04.001
Li J et al (2019) Relationship between cumulative exposure to pesticides and sleep disorders among greenhouse vegetable farmers. BMC Public Health 19:1–11. https://doi.org/10.1186/s12889-019-6712-6
Machado AKF et al (2018) Sleep problems and associated factors in a rural population of a Southern Brazilian city. Revista de Saúde Pública. https://doi.org/10.11606/s1518-8787.2018052000260
McDermott M et al (2018) Sleep disorders and the risk of stroke. Expert Rev Neurother 18:523–531. https://doi.org/10.1080/14737175.2018.1489239
NCHS, 2020. NHANES questionnaires, datasets, and related documentation Center Health Stat. https://wwwn.cdc.gov/nchs/nhanes/Default.aspx.
O’Brien KM et al (2016) Environmental chemicals in urine and blood: improving methods for creatinine and lipid adjustment. Environ Health Perspect 124:220–227. https://doi.org/10.1289/ehp.1509693
Park J et al (2019) Environmental pyrethroid exposure and diabetes in U.S. adults. Environ Res 172:399–407. https://doi.org/10.1016/j.envres.2018.12.043
Pizza F et al (2010) Sleep quality and motor vehicle crashes in adolescents. J Clin Sleep Med 6:41–45
Popovska-Gorevski M et al (2017) Carbamate insecticides target human melatonin receptors. Chem Res Toxicol 30:574–582. https://doi.org/10.1021/acs.chemrestox.6b00301
Ryan S (2018) Sleep and diabetes. Curr Opin Pulm Med 24:555–560. https://doi.org/10.1097/mcp.0000000000000524
Saillenfait AM et al (2015) Pyrethroids: exposure and health effects—an update. Int J Hyg Environ Health 218:281–292. https://doi.org/10.1016/j.ijheh.2015.01.002
Sánchez-López AM et al (2020) Childhood obesity and its influence on sleep disorders: kids-play study. Int J Environ Res Public Health. https://doi.org/10.3390/ijerph17217948
Saydah S et al (2014) Trends in cardiovascular disease risk factors by obesity level in adults in the United States, NHANES 1999–2010. Obesity (Silver Spring) 22:1888–1895. https://doi.org/10.1002/oby.20761
Sharma P et al (2014) Pyrethroid as a substance of abuse. Case Rep Psychiatry. https://doi.org/10.1155/2014/169294
Sun H et al (2007) Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay. Chemosphere 66:474–479. https://doi.org/10.1016/j.chemosphere.2006.05.059
Tsuji R et al (2012) Mammal toxicology of synthetic pyrethroids. Top Curr Chem 314:83–111. https://doi.org/10.1007/128_2011_269
Ueyama J et al (2010) Toxicokinetics of pyrethroid metabolites in male and female rats. Environ Toxicol Pharmacol 30:88–91. https://doi.org/10.1016/j.etap.2010.03.017
Vijverberg HP, van den Bercken J (1990) Neurotoxicological effects and the mode of action of pyrethroid insecticides. Crit Rev Toxicol 21:105–126. https://doi.org/10.3109/10408449009089875
Wagner-Schuman M et al (2015) Association of pyrethroid pesticide exposure with attention-deficit/hyperactivity disorder in a nationally representative sample of U.S. children. Environ Health 14:44. https://doi.org/10.1186/s12940-015-0030-y
Wetter DW et al (1994) Smoking as a risk factor for sleep-disordered breathing. Arch Intern Med 154:2219–2224. https://doi.org/10.1001/archinte.1994.00420190121014
Wittert G (2014) The relationship between sleep disorders and testosterone in men. Asian J Androl 16:262–265. https://doi.org/10.4103/1008-682x.122586
Yang CK et al (2005) Age-related changes in sleep/wake patterns among Korean teenagers. Pediatrics 115:250–256. https://doi.org/10.1542/peds.2004-0815G
Zamora AN et al (2021) Association between pesticide exposure and sleep health among a representative sample of US adults: evidence from NHANES 2009–2014. BMC Public Health 21:1–12. https://doi.org/10.1186/s12889-021-12014-x
Zamora AN et al (2022) Prenatal maternal pesticide exposure in relation to sleep health of offspring during adolescence. Environ Res 204:111977. https://doi.org/10.1016/j.envres.2021.111977
Zhorov BS, Dong K (2017) Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel. Neurotoxicology 60:171–177. https://doi.org/10.1016/j.neuro.2016.08.013
Zuo L et al (2022) Pyrethroids exposure induces obesity and cardiometabolic diseases in a sex-different manner. Chemosphere 291:132935. https://doi.org/10.1016/j.chemosphere.2021.132935