Severe thrombocytopaenia secondary to COVID-19

BMJ Case Reports - Tập 13 Số 9 - Trang e237645 - 2020
Trupesh Patel1, Noah J. Stanton1, Ioannis Gkikas2, Diana Triantafyllopoulou3
1Department of Medicine, Royal Blackburn Teaching Hospital, Blackburn, Lancashire, UK
2Gastroenterology, Royal Blackburn Teaching Hospital, Blackburn, Lancashire, UK
3Haematology, Royal Blackburn Teaching Hospital, Blackburn, Lancashire, UK

Tóm tắt

The SARS-CoV-2 infection has caused a pandemic with a case rate of over 290 000 lab-confirmed cases and over 40 000 deaths in the UK. There is little evidence to inform the optimal management of a patient presenting with new or relapsed acute idiopathic thrombocytopaenic purpura with concurrent SARS-CoV-2 infection. We present a case of severe thrombocytopaenia complicated by subdural haematoma and rectal bleed associated with COVID-19. A 67-year-old man, admitted with a non-productive cough and confusion, was found to be positive for COVID-19. Ten days after admission, his platelets decreased from 146×109/L to 2×109/L. His platelets did not increase despite receiving frequent platelet transfusions. He was non-responsive to corticosteroids and intravenous immunoglobulins. Romiplostim and eltrombopag were given and after 9 weeks of treatment, his platelet count normalised. He was deemed medically fit with outpatient follow-up in a haematology clinic.

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BMJ Case Reports

Tập 13 Số 9

e237645

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