Serum IgG and total protein concentrations in dairy calves fed two colostrum replacement products

Journal of the American Veterinary Medical Association - Tập 229 Số 8 - Trang 1282-1285 - 2006
Derek M. Foster1, Geoffrey Smith, Truman R. Sanner, Gonzalo V. Busso
1Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA

Tóm tắt

Abstract Objective—To evaluate effects of 2 commercially available colostrum replacement products on serum IgG and total protein concentrations in dairy calves. Design—Prospective clinical trial. Animals—84 Holstein bull calves from a single dairy. Procedures—Calves were randomly assigned to be given 4 quarts of colostrum (group 1; n = 21), 2 packages of a colostrum replacement product (product A; group 2; 21), 1 package of a different colostrum replacement product (product B; group 3; 21), or 2 packages of product B (group 4; 21). Treatments were given within 3 hours after birth, and blood samples were collected 24 hours later and submitted for determination of serum total protein and IgG concentrations. Results—Group 1 calves had significantly higher serum total protein and IgG concentrations than did calves in the other 3 groups. However, the percentage of calves with adequate passive transfer (ie, serum IgG concentration > 1,000 mg/dL) was not significantly different among groups 1 (90%), 3 (81%), and 4 (95%). In contrast, only 10% of calves in group 2 had adequate passive transfer. It was predicted that calves fed product B that had serum total protein concentrations > 5.2 g/dL would have serum IgG concentrations > 1,000 mg/dL at least 90% of the time. Conclusions and Clinical Relevance—Results indicated that product B could be considered as an alternative to colostrum in dairy calves, but product A failed to routinely provide adequate serum IgG concentrations when fed according to label directions.

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Tài liệu tham khảo

Weaver, 2000, Passive transfer of colostral immunoglobulins to calves, 14, 569, 10.1111/j.1939-1676.2000.tb02278.x

McGuire, 1982, Failure of colostral immunoglobulin transfer to calves: prevalence and diagnosis, 4, S35

McGuirk, 2004, Managing the production, storage, and delivery of colostrum, 20, 593, 10.1016/j.cvfa.2004.06.005

Quigley, 2002, Absorption of protein and IgG in calves fed a colostrum supplement or replacer, 85, 1243, 10.3168/jds.S0022-0302(02)74188-X

Jones, 2004, Influence of pooled colostrum or colostrum replacement on IgG and evaluation of animal plasma in milk replacer, 87, 1806, 10.3168/jds.S0022-0302(04)73337-8

Quigley, 2001, Formulation of colostrum supplements, colostrum replacers, and acquisition of passive immunity in neonatal calves, 84, 2059, 10.3168/jds.S0022-0302(01)74650-4

Zaremba, 1993, Efficacy of a dried colostrum powder in the prevention of disease in neonatal Holstein calves, 76, 831, 10.3168/jds.S0022-0302(93)77408-1

Garry, 1996, Comparison of passive immunoglobulin transfer to dairy calves fed colostrum or commercially available colostral-supplement products, 208, 107

Mee, 1996, Effect of a whey protein concentrate used as a colostrum substitute or supplement on calf immunity, weight gain, and health, 79, 886, 10.3168/jds.S0022-0302(96)76437-8

Hopkins, 1997, Effects of method of colostrum feeding and colostrum supplementation on concentrations of immunoglobulin G in the serum of neonatal calves, 80, 979, 10.3168/jds.S0022-0302(97)76023-5

Arthington, 2000, Effect of dietary IgG source (colostrum, serum, or milk-derived supplement) on the efficiency of Ig absorption in newborn Holstein calves, 83, 1463, 10.3168/jds.S0022-0302(00)75018-1

Etzel, 1997, Development of an automated turbidometric immunoassay for quantification of bovine serum immunoglobulin G, 58, 1201

Chelack, 1993, Evaluation of methods for dehydration of bovine colostrum for total replacement of normal colostrum in calves, 34, 407

Davenport, 2000, Addition of casein or whey protein to colostrum or a colostrum supplement product on absorption of IgG in neonatal calves, 83, 2813, 10.3168/jds.S0022-0302(00)75180-0

Muller, 1981, Colostral immunoglobulin concentrations among breeds of dairy cattle, 64, 1727, 10.3168/jds.S0022-0302(81)82754-3

Pritchett, 1991, Management and production factors influencing immunoglobulin G1 concentration in colostrum from Holstein cows, 74, 2336, 10.3168/jds.S0022-0302(91)78406-3

Moore, 2005, Effect of delayed colostrum collection on colostral IgG concentration in dairy cows, 226, 1375, 10.2460/javma.2005.226.1375

Morin, 2001, Factors associated with colostral specific gravity in dairy cows, 84, 937, 10.3168/jds.S0022-0302(01)74551-1

Maunsell, 1999, Use of mammary gland and colostral characteristics for prediction of colostral IgG1 concentration and intramammary infection in Holstein cows, 214, 1817

Franklin, 2003, Health and performance of Holstein calves that suckled or were hand-fed colostrum and were fed one of three physical forms of starter, 86, 2145, 10.3168/jds.S0022-0302(03)73804-1

Tyler, 1999, Colostral immunoglobulin concentrations in Holstein and Guernsey cows, 60, 1136

Burton, 1989, Variation in serum concentrations of immunoglobulins G, A, and M in Canadian Holstein-Friesian calves, 72, 135, 10.3168/jds.S0022-0302(89)79089-5

Gay, 1983, Seasonal variation in passive transfer of immunoglobulin G1 to newborn calves, 183, 566

Adams, 1985, Two methods for administering colostrum to newborn calves, 68, 773, 10.3168/jds.S0022-0302(85)80887-0

Holloway, 2001, Serum immunoglobulin G concentrations in calves fed fresh and frozen colostrum, 219, 357, 10.2460/javma.2001.219.357

Tyler, 1998, Use of serum protein concentration to predict mortality in mixed-source dairy replacement heifers, 12, 79, 10.1111/j.1939-1676.1998.tb02099.x

Robison, 1988, Effects of passive immunity on growth and survival in the dairy heifer, 71, 1283, 10.3168/jds.S0022-0302(88)79684-8

DeNise, 1989, Effects of passive immunity on subsequent production in dairy heifers, 72, 552, 10.3168/jds.S0022-0302(89)79140-2

Rea, 1996, Prediction of calf mortality by use of tests for passive transfer of colostral immunoglobulin, 208, 2047

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Journal of the American Veterinary Medical Association

Tập 229 Số 8

1282-1285

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