Serological Investigation of Corynebacterium Pseudotuberculosis Infection in Sheep–Correlation between the Hemolysis Inhibition Test and the ELISA Test
Tóm tắt
Corynebacterium pseudotuberculosis causes caseous lymphadenitis in sheep and goats. The animals may be infected without showing clinical symptoms. Several serotests have therefore been employed to detect infected animals. Shen et al (1982) performed an enzyme linked immunosorbent assay (ELISA) to detect antibodies against the organism using cell wall antigens. Maki et al (1985) found that the toxin of the bacterium was a better antigen for assessing infection in the ELISA test. They reported that the antitoxin ELISA appeared to be as sensitive as the antihemolysin inhibition test (Zaki 1968).
Tài liệu tham khảo
Holstad G: Corynebacterium pseudotuberculosis infection in goats. I. Evaluation of two serological diagnostic tests. Acta vet. scand. 1986, 27, 575–583.
Maki LR, Shen SH, Bergstrom RC, Stetzenbach LD: Diagnosis of Corynebacterium pseudotuberculosis infections in sheep, using an enzyme-linked immunosorbent assay. Amer. J. vet. Res. 1985, 46, 212–214.
Shen DT, Jen LW, Gorham JR: The detection of Corynebacterium pseudotuberculosis antibody in goats by the Enzyme-Linked Immunosorbent Assay (ELISA). Proc. 3rd. Int. Conf. Goat Prod. Dis. Tucson, Arizona 1982, pp. 445–448.
Zaki MM: The application of a new technique for diagnosis Corynebacterium ovis infection. Res. Vet. Sci. 1968, 9, 489–493.