Serial Position Curve in Rats: Role of the Dorsal Hippocampus

American Association for the Advancement of Science (AAAS) - Tập 218 Số 4568 - Trang 173-175 - 1982
Raymond P. Kesner1, Jeanne M. Novak1
1Department of Psychology, University of Utah, Salt Lake City 84112.

Tóm tắt

In an eight-arm radial maze, normal rats demonstrated good immediate retention for the order of first items (primacy component of serial position curve) and last items (recency component of serial position curve) of an eight-item (arm) list. In contrast, rats with dorsal hippocampal lesions displayed, on an immediate retention test, disruption of the primacy but not the recency component of the serial position curve. Furthermore, imposing a 10-minute delay before the retention test impaired all components of the serial position curve. These results support correspondence in mnemonic function of the hippocampus in animals and humans.

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Tài liệu tham khảo

BADDELEY, A.D., J VERB LEARN VERB BE 9: 76 (1970).

10.1126/science.7414331

HOREL, J.A., NEUROANATOMY OF AMNESIA - CRITIQUE OF HIPPOCAMPAL MEMORY HYPOTHESIS, BRAIN 101: 403 (1978).

IVERSEN, S.D., INTERNATIONAL REVIEW OF NEUROBIOLOGY 19: 1 (1976).

KINSBOURNE M SHORT TERM MEMORY (1975).

KONIG JFR RAT BRAIN STEREOTAXI (1963).

MILNER B CEREBRAL CORRELATES (1978).

MISHKIN, M, MEMORY IN MONKEYS SEVERELY IMPAIRED BY COMBINED BUT NOT BY SEPARATE REMOVAL OF AMYGDALA AND HIPPOCAMPUS, NATURE 273: 297 (1978).

OLTON, D.S., REMEMBRANCE OF PLACES PASSED - SPATIAL MEMORY IN RATS, JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL BEHAVIOR PROCESSES 2: 97 (1976).

OLTON, D.S., HIPPOCAMPAL FUNCTION - WORKING MEMORY OR COGNITIVE MAPPING, PHYSIOLOGICAL PSYCHOLOGY 8: 239 (1980).

TULVING E ORG MEMORY (1972).