Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Akiba, 1985, Ring transformation equilibrium (bond switch) in 5-(2-aminovinyl)isothiazole system via hypervalent sulfurane. synthesis, structure determination, and kinetic study, Journal of the American Chemical Society, 107, 2721, 10.1021/ja00295a026
Altschul, 1990, Basic local alignment search tool, Journal of Molecular Biology, 215, 403, 10.1016/S0022-2836(05)80360-2
Andrei, 1999, The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles, Molecular Biology of the Cell, 10, 1463, 10.1091/mbc.10.5.1463
Bach, 2001, Mucolipidosis type IV, Molecular Genetics and Metabolism, 73, 197, 10.1006/mgme.2001.3195
Bala, 2012, Synthesis Of 2-[4-(Substituted Benzylidene)-5-Oxo-4,5-Dihydro-Oxazol-2-Ylmethyl]-Isoindole-1,3-Dione derivatives as novel potential antimicrobial agents, Iranian Journal of Pharmacology and Therapeutics, 2012, 45
Bansode, 2009, Synthesis and antimicrobial activity of some new N-acyl substituted phenothiazines, European Journal of Medicinal Chemistry, 44, 5094, 10.1016/j.ejmech.2009.07.006
Cang, 2013, mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state, Cell, 152, 778, 10.1016/j.cell.2013.01.023
Cerri, 1974, Dihydro-1,2-oxazole Derivatives. Part IX 1 . Stereoselective Synthesis of Tetrahydro-1,2-oxazoles by Sodium Borohydride Reduction of 4,5-Dihydro-1,2-oxazolium Tetrafluoroborates, Synthesis, 1974, 710, 10.1055/s-1974-23410
Chen, 2007, Effect of tetrahydroquinoline dyes structure on the performance of organic dye-sensitized solar cells, Chemistry of Materials, 19, 4007, 10.1021/cm070617g
Chen, 2014, A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV, Nature Communications, 5, 4681, 10.1038/ncomms5681
Chen, 2017, Small Molecules for Early Endosome-Specific Patch Clamping, Cell Chemical Biology, 24, 907, 10.1016/j.chembiol.2017.05.025
Chen, 2017, Structure of mammalian endolysosomal TRPML1 channel in nanodiscs, Nature, 550, 415, 10.1038/nature24035
Chen, 2017, Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes, Nature Protocols, 12, 1639, 10.1038/nprot.2017.036
Choudhury, 2002, Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells, Journal of Clinical Investigation, 109, 1541, 10.1172/JCI0215420
Cuajungco, 2016, The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function, Pflügers Archiv - European Journal of Physiology, 468, 177, 10.1007/s00424-015-1732-2
Daly, 2003, Monocyte chemoattractant protein-1 (CCL2) in inflammatory disease and adaptive immunity: therapeutic opportunities and controversies, Microcirculation, 10, 247, 10.1080/mic.10.3-4.247.257
Deshmane, 2009, Monocyte chemoattractant protein-1 (MCP-1): an overview, Journal of Interferon & Cytokine Research, 29, 313, 10.1089/jir.2008.0027
Dong, 2010, PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome, Nature Communications, 1, 1, 10.1038/ncomms1037
Escudero, 2011, Efficient Cesium Carbonate Promoted N-Alkylations of Aromatic Cyclic Imides Under Microwave Irradiation, Synthesis, 2011, 571, 10.1055/s-0030-1258398
Fos, 1992, Synthesis of isomeric series of aryltetrahydrobenz-isoxazoles and arylcyclopentisoxazoles, Journal of Heterocyclic Chemistry, 29, 203, 10.1002/jhet.5570290137
García-Añoveros, 2014, TRPML2 and mucolipin evolution, Handbook of experimental pharmacology, 222, 647, 10.1007/978-3-642-54215-2_25
Grimm, 2010, Small molecule activators of TRPML3, Chemistry & Biology, 17, 135, 10.1016/j.chembiol.2009.12.016
Grimm, 2012, Role of TRPML and two-pore channels in endolysosomal cation homeostasis, Journal of Pharmacology and Experimental Therapeutics, 342, 236, 10.1124/jpet.112.192880
Grimm, 2012, Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules, Journal of Biological Chemistry, 287, 22701, 10.1074/jbc.M112.369876
Grimm, 2014, High susceptibility to fatty liver disease in two-pore channel 2-deficient mice, Nature Communications, 5, 4699, 10.1038/ncomms5699
Grimm, 2016, Endolysosomal cation channels as therapeutic targets—pharmacology of TRPML channels, Messenger, 5, 30, 10.1166/msr.2016.1061
Hirschi, 2017, Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3, Nature, 550, 411, 10.1038/nature24055
Hruz, 2011, RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization, BMC Genomics, 12, 156, 10.1186/1471-2164-12-156
Huisgen, 1963, 1.3-Dipolare cycloadditionen rückschau und ausblick, Angewandte Chemie, 75, 604, 10.1002/ange.19630751304
Jawalekar, 2011, Synthesis of isoxazoles by hypervalent iodine-induced cycloaddition of nitrile oxides to alkynes, Chemical Communications, 47, 3198, 10.1039/c0cc04646a
Jörs, 2010, Genetic Inactivation of Trpml3 Does Not Lead to Hearing and Vestibular Impairment in Mice, PLoS ONE, 5, e14317, 10.1371/journal.pone.0014317
Karacsonyi, 2007, Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs, Traffic, 8, 1404, 10.1111/j.1600-0854.2007.00619.x
Kim, 2009, The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy, Traffic, 10, 1157, 10.1111/j.1600-0854.2009.00924.x
Kuehne, 1964, Enamines as 1,3-Dipolarophiles1, The Journal of Organic Chemistry, 29, 1582, 10.1021/jo01029a075
Lacy, 2011, Cytokine release from innate immune cells: association with diverse membrane trafficking pathways, Blood, 118, 9, 10.1182/blood-2010-08-265892
LaPlante, 2006, Lysosomal exocytosis is impaired in mucolipidosis type IV, Molecular Genetics and Metabolism, 89, 339, 10.1016/j.ymgme.2006.05.016
Lelouvier, 2011, Mucolipin-3 regulates luminal calcium, acidification, and membrane fusion in the endosomal pathway, Journal of Biological Chemistry, 286, 9826, 10.1074/jbc.M110.169185
Li, 2013, One-Pot Synthesis of Indolo[2,3-c]quinolin-6-ones by Sequential Photocyclizations of 3-(2-Azidophenyl)-N-phenylacrylamides, Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry, 24, 73, 10.1055/s-0032-1317703
Li, 2016, A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation, Nature Cell Biology, 18, 404, 10.1038/ncb3324
Li, 2017, Structural basis of dual Ca2+/pH regulation of the endolysosomal TRPML1 channel, Nature Structural & Molecular Biology, 24, 205, 10.1038/nsmb.3362
Lopez-Castejon, 2011, Understanding the mechanism of IL-1β secretion, Cytokine & Growth Factor Reviews, 22, 189, 10.1016/j.cytogfr.2011.10.001
Manderson, 2007, Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha, The Journal of Cell Biology, 178, 57, 10.1083/jcb.200612131
Miao, 2015, A TRP channel senses lysosome neutralization by pathogens to trigger their expulsion, Cell, 161, 1306, 10.1016/j.cell.2015.05.009
Murray, 2014, Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking, Frontiers in Immunology, 5, 538, 10.3389/fimmu.2014.00538
Park, 2016, Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV, EMBO reports, 17, 266, 10.15252/embr.201541542
Pryor, 2006, Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic, Traffic, 7, 1388, 10.1111/j.1600-0854.2006.00475.x
Rinkenberger, 2018, Mucolipin-2 Cation Channel Increases Trafficking Efficiency of Endocytosed Viruses, mBio, 9, 10.1128/mBio.02314-17
Samie, 2013, A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis, Developmental Cell, 26, 511, 10.1016/j.devcel.2013.08.003
Schmiege, 2017, Human TRPML1 channel structures in open and closed conformations, Nature, 550, 366, 10.1038/nature24036
Shen, 2012, Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release, Nature Communications, 3, 731, 10.1038/ncomms1735
Shen, 2006, Statistical potential for assessment and prediction of protein structures, Protein Science, 15, 2507, 10.1110/ps.062416606
Soyombo, 2006, TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity, Journal of Biological Chemistry, 281, 7294, 10.1074/jbc.M508211200
Sun, 2015, Novel Role of TRPML2 in the regulation of the innate immune response, The Journal of Immunology, 195, 4922, 10.4049/jimmunol.1500163
Tagle, 2017, Silicon-containing halogenated poly(amides) derived from diacids with aminoacidic and imidic moieties in the side chain: synthesis, characterization, optical studies and thermal properties, Polymer Bulletin, 74, 263, 10.1007/s00289-016-1714-3
Tan, 2004, Structure-based de novo design of ligands using a three-dimensional model of the insulin receptor, Bioorganic & Medicinal Chemistry Letters, 14, 1407, 10.1016/j.bmcl.2004.01.064
The UniProt Consortium, 2017, UniProt: the universal protein knowledgebase, Nucleic Acids Research, 45, D158, 10.1093/nar/gkw1099
Valadez, 2015, PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene, Gene, 555, 194, 10.1016/j.gene.2014.11.003
Venkatachalam, 2006, Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1, Journal of Biological Chemistry, 281, 17517, 10.1074/jbc.M600807200
Venkatachalam, 2013, Feast or famine: role of TRPML in preventing cellular amino acid starvation, Autophagy, 9, 98, 10.4161/auto.22260
Venturini I, Filippini L, Vazzola MS. 2010. Benzamidic compounds having fungicidal activity and relative use. World Intellectual Property Organization. WO2010109301A1. https://patents.google.com/patent/WO2010109301A1/enGo.
Venugopal, 2007, Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV, The American Journal of Human Genetics, 81, 1070, 10.1086/521954
Vergarajauregui, 2009, Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1, Journal of Biological Chemistry, 284, 36357, 10.1074/jbc.M109.047241
Vitale, 2013, Functional 3-Arylisoxazoles and 3-Aryl-2-isoxazolines from Reaction of Aryl Nitrile Oxides and Enolates: Synthesis and Reactivity, Synthesis, 45, 2940, 10.1055/s-0033-1338540
Volkov, 2014, Catalytic reductive dehydration of tertiary amides to enamines under hydrosilylation conditions, Organic Letters, 16, 680, 10.1021/ol403302g
Wang, 2012, TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes, Cell, 151, 372, 10.1016/j.cell.2012.08.036
Webb, 2014, Comparative protein structure modeling using MODELLER, Current Protocols in Bioinformatics, 47, 5.6.1, 10.1002/0471250953.bi0506s47
Wulfman, 1988, The synthesis of ahyl diazomethanes, Synthetic Communications, 18, 2349, 10.1080/00397918808082380
Xia, 2009, Recent developments in CCR2 antagonists, Expert Opinion on Therapeutic Patents, 19, 295, 10.1517/13543770902755129
Yamaguchi, 2010, Opening the TRPML gates, Chemistry & Biology, 17, 209, 10.1016/j.chembiol.2010.02.009
Zhang, 2017, Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism, Protein & Cell, 8, 834, 10.1007/s13238-017-0476-5