Segmental expression of the T‐box transcription factor, Tbx2, during early somitogenesis

Developmental Dynamics - Tập 235 Số 11 - Trang 3080-3084 - 2006
Zachary Harrelson1, Virginia E. Papaioannou1
1Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, New York.

Tóm tắt

Abstract

Tbx2 belongs to the T‐box transcription factor gene family and is expressed in a variety of tissues and structures throughout development, although not all expression domains have been thoroughly described. Two areas of segmented expression along the rostral‐caudal axis of E10.5–11.5 embryos were identified as inter‐somitic vessels and dorsal root ganglia. In addition, Tbx2 expression is observed during somitogenesis beginning at E9.5, both in the posterior half of prospective somites and in a progressively restricted pattern in recently formed somites. Developmental Dynamics 235:3080–3084, 2006. © 2006 Wiley‐Liss, Inc.

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