Screening Station, a novel laboratory automation system for physiologically relevant cell-based assays

SLAS Technology - Tập 28 - Trang 351-360 - 2023
Ichiji Namatame1, Kana Ishii1, Takashi Shin1, Daisuke Shimojo1, Yukiko Yamagishi1,2, Hidemitsu Asano3, Yuuki Kishimoto4, Hiromitsu Fuse2, Yohei Nishi2, Hidetoshi Sakurai2, Tatsutoshi Nakahata2, Haruna Sasaki-Iwaoka1
1Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan
2Center for iPS Cell Research and Application (CiRA), Kyoto University, 53, Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan
3Rorze Lifescience Inc., 430-1, Kamiyokoba, Tsukuba-shi, Ibaraki, 305-0854, Japan
4Yokogawa Electric Co., 2-9-32, Naka-machi, Musashino-shi, Tokyo, 180-8750, Japan

Tài liệu tham khảo

Egawa, 2012, Drug screening for ALS using patient-specific induced pluripotent stem cells, Sci Trans Med, 4, 10.1126/scitranslmed.3004052 Fujimori, 2018, Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent, Nat Med, 24, 1579, 10.1038/s41591-018-0140-5 Yahata, 2011, Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease, PLoS ONE, 6, e25788, 10.1371/journal.pone.0025788 Kondo, 2017, iPSC-based compound screening and in vitro trials identify a synergistic anti-amyloid Β combination for Alzheimer's disease, Cell Rep, 21, 2304, 10.1016/j.celrep.2017.10.109 Kokubu, 2019, Phenotypic drug screening for dysferlinopathy using patient-derived induced pluripotent stem cells, Stem Cells Trans Med, 8, 1017, 10.1002/sctm.18-0280 Huang, 2021, Human pluripotent stem cell-derived cardiac cells: application in disease modeling, cell therapy, and drug discovery, front, Cell Dev Biol, 9 Holland, 2020, Automation in the life science research laboratory, Front Boing Bioethanol, 8 Fleischer, 2020, On the way to efficient analytical measurements: the future of robot-based measurements, SLAS Tech, 25, 208, 10.1177/2472630319886270 Sasamata, 2021, Establishment of a robust platform for induced pluripotent stem cell research using Maholo LabDroid, SLAS Tech, 26, 441, 10.1177/24726303211000690 Basal, 2021, Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia, Nature Commun, 5220, 1 Doulgkeroglou, 2020, Automation, monitoring, and standardization of cell product manufacturing, Front Bioeng Biotechnol, 8, 811, 10.3389/fbioe.2020.00811 Ochs, 2021, Fully automated cultivation of adipose-derived stem cells in the StemCellDiscovery—a robotic laboratory for small-scale, high-throughput cell production including deep learning-based confluence estimation, Processes, 9, 575, 10.3390/pr9040575 Wardwell-Swanson, 2020, A framework for optimizing high-content imaging of 3D models for drug discovery, SLAS Discov, 25, 709, 10.1177/2472555220929291 Itoh, 2021, Optimal scheduling for laboratory automation of life science experiments with time constraints, SLAS Tech, 26, 650, 10.1177/24726303211021790 Zucchelli, 2021, Highly versatile cloud-based automation solution for the remote design and execution of experiment protocols during the COVID-19 pandemic, SLAS Tech, 26, 127, 10.1177/2472630320971218 Sasaki-Honda, 2018, A patient- derived iPSC model revealed oxidative stress increases facioscapulohumeral muscular Dystrophy-Causative Dux4, Human Mol Gen, 27, 4024, 10.1093/hmg/ddy293 Uchimura, 2017, A human iPS cell myogenic differentiation system permitting high-throughput drug screening, Stem Cell Res, 25, 98, 10.1016/j.scr.2017.10.023 Lehmann, 2016, Biomek cell workstation: a variable system for automated cell cultivation, J Lab Autom, 21, 439, 10.1177/2211068215599786 Manna, 2011, High-throughput quantification of bioactive lipids by MALDI mass spectrometry: application to prostaglandins, Anal Chem, 83, 6683, 10.1021/ac201224n Bray, 2016, Cell painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes, Nature Protocols, 9, 1757, 10.1038/nprot.2016.105 Yachie, 2017, Robotic crowd biology with Maholo Labdroids, Nature Biotech, 35, 310, 10.1038/nbt.3758