Safety Assessment of Diethanolamine and Its Salts as Used in Cosmetics

International Journal of Toxicology - Tập 36 Số 5_suppl2 - Trang 89S-110S - 2017
Monice Fiume1, Bart Heldreth2, Wilma F. Bergfeld3, D. Belsito3, Ronald A. Hill3, Curtis D. Klaassen3, D.C. Liebler3, James G. Marks3, Ronald C. Shank3, Thomas J. Slaga3, Paul W. Snyder3, F. Alan Andersen4
1Senior Director, Cosmetic Ingredient Review, Washington, DC, USA
2Executive Director, Cosmetic Ingredient Review, Washington, DC, USA
3Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA
4Former Director, Cosmetic Ingredient Review, Washington, DC, USA

Tóm tắt

The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of diethanolamine and its salts as used in cosmetics. Diethanolamine functions as a pH adjuster; the 16 salts included in this rereview reportedly function as surfactants, emulsifying agents, viscosity increasing agents, hair or skin conditioning agents, foam boosters, or antistatic agents. The Panel reviewed available animal and clinical data, as well as information from previous CIR reports. Since data were not available for each individual ingredient, and since the salts dissociate freely in water, the Panel extrapolated from previous reports to support safety. The Panel concluded that diethanolamine and its salts are safe for use when formulated to be nonirritating. These ingredients should not be used in cosmetic products in which N-nitroso compounds can be formed.

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International Journal of Toxicology

Tập 36 Số 5_suppl2

89S-110S

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