Vu Huu Vinh1, Nguyen Viet Dang Quang1, Nguyen Van Nam2
1Thoracic Department, Cho Ray Hospital
2Cardiovascular - Thoracic Department, Military Hospital 103

Tóm tắt

Objectives: To evaluate the efficacy of robotic video-assisted thoracic lobectomy (r-VATS) in patients with locally advanced non-small cell lung cancer. Subjects and methods: r-VATS lobectomy was performed in 79 patients with non-small cell lung cancer treated at Cho Ray Hospital from July 2018 to June 2022. We divided 79 patients into two groups: Group 1 consists of 50 patients with tumors < 5 cm in diameter; group 2 consists of 29 patients with tumors ≥ 5 cm in diameter (cT3 and cT4). Results: The mean operative time of the tumor ≥ 5 cm group was longer than that of the other group (273.7 minutes vs. 255.5 minutes); however, the difference was not statistically significant. The rate of conversion to open surgery in group 2 was significantly higher than in group 1 (17.2% vs. 4.0%, p = 0.046). There was no statistically significant difference in post-operative complications in the two groups. There was no significant difference in the survival rate in the two groups (p = 0.272). Conclusion: r-VATS is effective in lobectomy for non-small cell lung cancer  ≥ 5 cm in size (cT3 and cT4). With tumor size ≥ 5 cm, the surgical time, the rate of postoperative complications, and the post-operative recurrence rate did not increase; however, the conversion rate to open surgery increased.

Tài liệu tham khảo

Morgensztern D., Ng S.H., Gao F., et al. (2010). Trends in stage distribution for patients with non-small cell lung cancer: A National Cancer Database survey. J Thorac Oncol; 5: 29-33. Glover J., Velez-Cubian F.O., Toosi K., et al. (2016). Perioperative outcomes and lymph node assessment after induction therapy in patients with clinical N1 or N2 non-small cell lung cancer. J Thorac Dis; 8: 2165-2174. [Crossref] [PubMed]. Parini, S., Massera, F., Papalia, E., et al. (2022). Placement Strategies for Robotic Pulmonary Lobectomy: A Narrative Review. J. Clin. Med; 11: 2612. jcm11092612. Veronesi G., Abbas A.E., Murianna P. et al. (2021). Perioperative outcome of robotic approach versus manual videothoracoscopic major resection in patients affected by early lung cancer: resultss od a randomized multicentric study (ROMAN study). Front Oncol; 11: 726408. Yang H.X., Woo K.M., Sima C.S., et al. (2016). Long term survival based on the surgical approach to lobectomy for clinical stage I nonsmall cell lung cancer: comparison of robotic, video-assisted thoracic surgery and thoracotomy lobectomy. Ann Surg; Kneuertz P.J., Singer E., D’Souza H., et al. (2019). Hospital cost and clinical effective- ness of robotic-assisted versus video-assisted thoracoscopic and open lobectomy: A propensity score-weighted comparison. J. Thorac. Cardiovasc. Surg; 157: 2018-2026.e2. Nelson D.B., Mehran R.J., Mitchell K.G., et al. (2019). Robotic-Assisted Lobectomy for Non-Small Cell Lung Cancer: A Comprehensive Institutional Experience. Ann. Thorac. Surg; 108: 370-376. Mao J., Tang Z., Mi Y., et al. (2021). Robotic and video-assisted lobectomy/segmentectomy for non-small cell lung cancer have similar perioperative outcomes: A systematic review and meta-analysis. Translational Cancer Research; 10(9): 3883-3893. Ma J., Li X., Zhao S., et al. (2021). Robot-assisted thoracic surgery versus video-assisted thoracic surgery for lung lobectomy or segmentectomy in patients with non - small cell lung cancer: A meta-analysis. BMC cancer; 21: 498. Toosi K., Velez-Cubian F.O., Glover J., et al. (2016). Upstaging and survival after robotic-assisted thoracoscopic lobectomy for non-small cell lung cancer. Surgery. 10.1016/j.surg.2016.08.003.