SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of β1-integrin
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Spiegelman, B. M. & Heinrich, R. Biological control through regulated transcriptional coactivators. Cell 119, 157–167 (2004).
Copeland, J. W. & Treisman, R. The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. Mol. Biol. Cell 13, 4088–4099 (2002).
Grosse, R., Copeland, J. W., Newsome, T P., Way, M. & Treisman, R. A role for VASP in RhoA-Diaphanous signalling to actin dynamics and SRF activity. EMBO J. 22, 3050–3061 (2003).
Cen, B. et al. Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol. Cell. Biol. 23, 6597–6608 (2003).
Miralles, F., Posern, G., Zaromytidou, A. I. & Treisman, R. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 113, 329–342 (2003).
Vartiainen, M. K., Guettler, S., Larijani, B. & Treisman, R. Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL. Science 316, 1749–1752 (2007).
Ma, Z. et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nature Genet. 28, 220–221 (2001).
Mercher, T. et al. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. Proc. Natl Acad. Sci. USA 98, 5776–5779 (2001).
Somogyi, K. & Rorth, P. Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration. Dev. Cell 7, 85–93 (2004).
DeMali, K. A., Wennerberg, K. & Burridge, K. Integrin signaling to the actin cytoskeleton. Curr. Opin. Cell Biol. 15, 572–582 (2003).
Brakebusch, C., Bouvard, D., Stanchi, F., Sakai, T. & Fassler, R. Integrins in invasive growth. J. Clin. Invest. 109, 999–1006 (2002).
Caswell, P. T. et al. Rab25 associates with α5β1-integrin to promote invasive migration in 3D microenvironments. Dev Cell 13, 496–510 (2007).
Brakebusch, C. & Fassler, R. β1-integrin function in vivo: adhesion, migration and more. Cancer Metastasis Rev. 24, 403–411 (2005).
Wang, W. et al. Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 64, 8585–8594 (2004).
White, D. E. et al. Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6, 159–170 (2004).
Yao, E. S. et al. Increased β1-integrin is associated with decreased survival in invasive breast cancer. Cancer Res. 67, 659–664 (2007).
Brandt, D. T. et al. Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation. J. Cell Biol. 178, 193–200 (2007).
Zaromytidou, A.-I., Miralles, F. & Treisman, R. MAL and Ternary Complex Factor use different mechanisms to contact a common surface on the Serum Response Factor DNA-binding domain. Mol. Cell. Biol. 26, 4134–4148 (2006).
Liu, Z. P., Wang, Z., Yanagisawa, H. & Olson, E. N. Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Dev. Cell 9, 261–270 (2005).
Kitzing, T. M. et al. Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev. 21, 1478–1483 (2007).
Wolf, K. et al. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 160, 267–277 (2003).
Spessotto, P. et al. β1-Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain. J. Biol. Chem. 278, 6160–6167 (2003).
Medjkane, S., Perez-Sanchez, C., Gaggioli, C., Sahai, E. & Treisman, R. Myocardin-related transcription factors and SRF are required for cytoskeleton dynamics and experimental metastasis. Nature Cell Biol. 11, 257–268 (2009).
Padua, D. et al. TGFβ primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133, 66–77 (2008).
Carreira, S. et al. Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev. 20, 3426–3439 (2006).
Phair, R. D. & Misteli, T. High mobility of proteins in the mammalian cell nucleus. Nature 404, 604–609 (2000).
Freddie, C. T., Ji, Z., Marais, A. & Sharrocks, A. D. Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF. Nucleic Acids Res. 35, 5203–5212 (2007).
Worzfeld, T., Puschel, A. W., Offermanns, S. & Kuner, R. Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development. Eur J. Neurosci. 19, 2622–2632 (2004).