SAMase of Bacteriophage T3 Inactivates Escherichia coli’s Methionine S -Adenosyltransferase by Forming Heteropolymers

mBio - Tập 12 Số 4 - 2021
Hadas Simon‐Baram1, Daniel Kleiner1, Fannia Shmulevich1, Raz Zarivach1,2, Ran Zalk3, Huayuan Tang4, Feng Ding4, Shimon Bershtein1
1Department of Life Sciences, Ben-Gurion University of the Negevgrid.7489.2, Beer-Sheva, Israel
2Macromolecular Crystallography and Cryo-EM Research Center, The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negevgrid.7489.2, Beer-Sheva, Israel
3Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negevgrid.7489.2, Beer-Sheva, Israel
4Department of Physics and Astronomy, Clemson Universitygrid.26090.3d, Clemson, South Carolina, USA

Tóm tắt

Self-assembly of enzymes into filamentous structures in response to specific metabolic cues has recently emerged as a widespread strategy of metabolic regulation. In many instances, filamentation of metabolic enzymes occurs in response to starvation and leads to functional inactivation.

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Tập 12 Số 4

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