Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition

Multiple Sclerosis Journal - Tập 26 Số 14 - Trang 1816-1821 - 2020
Clare Walton1, Rachel King1, Lindsay Rechtman2, Wendy Kaye2, Emmanuelle Leray3, Ruth Ann Marrie4, Neil Robertson5, Nicholas La Rocca6, Bernard M.J. Uitdehaag7, Ingrid van der Mei8, Mitchell T. Wallin9, Anne Helme1, Ceri Angood Napier1, Nick Rijke1, Peer Baneke1
1Multiple Sclerosis International Federation, London, UK
2McKing Consulting Corporation, Atlanta, GA USA
3EA 7449 REPERES, Epidemiology, Ecole des Hautes Etudes en Sante Publique, Rennes, France
4Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.
5Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, Cardiff, UK
6National MS Society, West Bath, ME, USA
7Neurology, Amsterdam UMC–Locatie VUMC, Amsterdam, Netherlands
8Menzies Research Institute, University of Tasmania, Hobart, Tas, Australia
9Department of Neurology, George Washington University, Washington, DC, USA

Tóm tắt

Background: High-quality epidemiologic data worldwide are needed to improve our understanding of disease risk, support health policy to meet the diverse needs of people with multiple sclerosis (MS) and support advocacy efforts. Objectives: The Atlas of MS is an open-source global compendium of data regarding the epidemiology of MS and the availability of resources for people with MS reported at country, regional and global levels. Methods: Country representatives reported epidemiologic data and their sources via survey between September 2019 and March 2020, covering prevalence and incidence in males, females and children, and age and MS type at diagnosis. Regional analyses and comparisons with 2013 data were conducted. Results: A total of 2.8 million people are estimated to live with MS worldwide (35.9 per 100,000 population). MS prevalence has increased in every world region since 2013 but gaps in prevalence estimates persist. The pooled incidence rate across 75 reporting countries is 2.1 per 100,000 persons/year, and the mean age of diagnosis is 32 years. Females are twice as likely to live with MS as males. Conclusions: The global prevalence of MS has risen since 2013, but good surveillance data is not universal. Action is needed by multiple stakeholders to close knowledge gaps.

Từ khóa


Tài liệu tham khảo

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10.1212/WNL.0b013e3182535cf6

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10.1177/1352458519861270

10.1016/S1474-4422(18)30443-5

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Thông tin xuất bản

Multiple Sclerosis Journal

Tập 26 Số 14

1816-1821

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