Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
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Bal, A.E. Variable expressivity of patched mutations in flies and humans. Am. J. Hum. Genet. 60, 10–12 (1997).
Hahn, H. et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85, 841–851 (1996).
Johnson, R.L. et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272, 1668–1671 (1996).
Pappo, A.S., Shapiro, D.N. & Crist, W.M. Rhabdomyosarcoma. Biology and treatment. Pediatr. Clin. North. Am. 44, 953–972 (1997).
Goodrich, L.V., Milenkovic, L., Higgins, K.M. & Scott, M.P. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277, 1109–1113 (1997).
Dahmane, N. et al. Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 389, 876–881 (1997).
Zhan, S. et al. Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer. J. Biol. Chem. 270, 27983–27986 (1995).
Hall, E.J. Effects of radiation on the embryo and fetus. In: Radiobiology for the radiologist (J.B. Lippincott Company,–Philadelphia, 1994).
Cossu, G., Tajbakhsh, S. & Buckingham, M. How is myogenesis initiated in the embryo? Trends Genet. 12, 218–23 (1996).
Hynes, M. et al. Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron 19, 15–26 (1997).
Albrecht, S. et al. Variable imprinting of H19 and IGF2 in fetal cerebellum and medulloblastoma. J. Neuropathol. Exp. Neurol. 55, 1270–1276 (1996).
Sun, F.L., Dean, W.L., Kelsey, G., Allen, N.D. & Reik, W. Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389, 809–815 (1997).
Shapiro, D.N., Sublett, J.E., Li, B., Downing, J.R. & Naeve, C.W. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 53, 5108–5112 (1993).
Rugh, R. The mouse: its reproduction and development (Oxford University Press, New-York, 1990).
Goodrich, L.V., Johnson, R.L., Milenkovic, L., McMahon, J.A. & Scott, M.P. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 10, 301–312 (1996).
Levanat, S. et al. A two-hit model for developmental defects in Gorlin syndrome. Nature Genet. 12, 85–87 (1996).
Arlett, C.F. & Priestley, A. Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains. Br. J. Cancer Suppl. 6, 227–232 (1984).
Featherstone, T., Taylor, A.M. & Harnden, D.G. Studies on the radiosensitivity of cells from patients with basal cell naevus syndrome. Am. J. Hum. Genet. 35, 58–66 (1983).