Retrospective study: the presence of<i>Malassezia</i>in feline skin biopsies. A clinicopathological study

Veterinary Dermatology - Tập 13 Số 1 - Trang 7-14 - 2002
Elizabeth A. Mauldin1, Daniel O. Morris1, Michael H. Goldschmidt1
1Departments of *Clinical Studies and †Pathobiology, Veterinary Hospital of the University of Pennsylvania, 3850 Spruce St. Philadelphia, PA 19104, USA

Tóm tắt

AbstractMalasseziaspp. dermatitis, a rare disorder in cats, has previously been associated with immune suppression and internal malignancies. This study evaluates the presence and importance ofMalasseziaspp. in feline biopsy specimens submitted for histopathological examination. Five hundred and fifty haematoxylin and eosin‐stained skin biopsy specimens received for histopathological examination between January 1999 and November 2000 were reviewed. Fifteen (2.7%) submissions containedMalasseziaorganisms in the stratum corneum of the epidermis or follicular infundibulum. Eleven of 15 cats presented with an acute onset of multifocal to generalized skin lesions. All 11 cats were euthanized or died within 2 months of the onset of clinical signs. Seven cats had dermatopathological changes and clinical signs supportive of paraneoplastic alopecia, and three cats had an interface dermatitis suggestive of erythema multiforme or thymoma‐associated dermatosis. Histopathological changes were nonspecific in one cat that was euthanized 2 weeks following onset of severe pruritus and alopecia. In three cats,Malasseziaspp. were found in localized sites (two chin, one footpads) and appeared inconsequential to their overall health status. One cat hadMalasseziaspp. in association with cutaneous demodicosis. These findings suggest thatMalasseziayeast in dermatopathological specimens from multifocal or generalized lesions should prompt a thorough clinical work‐up for internal neoplasia.

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Veterinary Dermatology

Tập 13 Số 1

7-14

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