Sự ngừng chu kỳ tế bào do axit retinoic gây ra ở các dòng tế bào myeloid người liên quan đến sự điều chỉnh giảm lần lượt của c-Myc và cyclin E cùng với sự điều chỉnh tăng sau phiên mã của p27Kip1

Sawyers, 1991, Leukemia and the disruption of normal hematopoiesis., Cell., 64, 337, 10.1016/0092-8674(91)90643-D Grana, 1995, Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)., Oncogene., 11, 211 Dyson, 1998, The regulation of E2F by pRB-family proteins., Genes Dev., 12, 2245, 10.1101/gad.12.15.2245 Brehm, 1998, Retinoblastoma protein recruits histone deacetylase to repress transcription., Nature., 391, 597, 10.1038/35404 Sherr, 1999, CDK inhibitors: positive and negative regulators of G1-phase progression., Genes Dev., 13, 1501, 10.1101/gad.13.12.1501 Vidal, 2000, Cell-cycle inhibitors: three families united by a common cause., Gene., 247, 1, 10.1016/S0378-1119(00)00092-5 Warrell, 1993, Acute promyelocytic leukemia [see comments]., N Engl J Med., 329, 177, 10.1056/NEJM199307153290307 Altucci, 2001, Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL., Nat Med., 7, 680, 10.1038/89050 Liu, 1996, Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation., J Biol Chem., 271, 31723, 10.1074/jbc.271.49.31723 Jiang, 1994, Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53., Oncogene., 9, 3397 Steinman, 1994, Induction of p21 (WAF-1/CIP1) during differentiation., Oncogene., 9, 3389 Sundstrom, 1976, Establishment and characterization of a human histiocytic lymphoma cell line (U-937)., Int J Cancer., 17, 565, 10.1002/ijc.2910170504 Nilsson, 1980, Differentiation in vitro of human leukemia and lymphoma cell lines., International Symposium on New Trends in Human Immunology and Cancer Immuno-therapy. Olsson, 1982, Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3′:5′-monophosphate-inducing agents., Cancer Res., 42, 3924 Olsson, 1983, Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1 alpha,25-dihydroxycholecalciferol., Cancer Res., 43, 5862 Larsson, 1991, c-jun is induced to high continuous expression during differentiation of hematopoietic cells and is regulated independently from c-fos., Leuk Lymphoma., 4, 193, 10.3109/10428199109068065 Collins, 1977, Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture., Nature., 270, 347, 10.1038/270347a0 Lanotte, 1991, NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)., Blood., 77, 1080, 10.1182/blood.V77.5.1080.1080 Larsson, 1988, Phorbol ester-induced terminal differentiation is inhibited in human U-937 monoblastic cells expressing a v-myc oncogene., Proc Natl Acad Sci U S A., 85, 2638, 10.1073/pnas.85.8.2638 Vindelov, 1983, A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis., Cytometry., 3, 323, 10.1002/cyto.990030503 Bahram, 1999, Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts., Blood., 93, 3900, 10.1182/blood.V93.11.3900 Miller, 1986, Regulated expression of the Mac-1, LFA-1, p150.95 glycoprotein family during leukocyte differentiation., J Immunol., 137, 2891, 10.4049/jimmunol.137.9.2891 Liu, 1996, Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937., Genes Dev., 10, 142, 10.1101/gad.10.2.142 Borriello, 2000, p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation: evidence of a decreased proteasome-dependent degradation., Oncogene., 19, 51, 10.1038/sj.onc.1203231 Knudsen, 1997, Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation., Mol Cell Biol., 17, 5771, 10.1128/MCB.17.10.5771 Knudsen, 1996, Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites., J Biol Chem., 271, 8313, 10.1074/jbc.271.14.8313 Lipinski, 1999, The retinoblastoma gene family in differentiation and development., Oncogene., 18, 7873, 10.1038/sj.onc.1203244 Grana, 1998, Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth., Oncogene., 17, 3365, 10.1038/sj.onc.1202575 Westin, 1982, Differential expression of the amv gene in human hematopoietic cells., Proc Natl Acad Sci U S A., 79, 2194, 10.1073/pnas.79.7.2194 Henriksson, 1996, Proteins of the Myc network: essential regulators of cell growth and differentiation., Adv Cancer Res., 68, 109, 10.1016/S0065-230X(08)60353-X Collins, 1987, The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression., Blood., 70, 1233, 10.1182/blood.V70.5.1233.1233 Brooks, 1997, An RXR-selective analog attenuates the RAR alpha-selective analog-induced differentiation and non-G1-restricted growth arrest of NB4 cells., Exp Cell Res., 234, 259, 10.1006/excr.1997.3620 Vlach, 1996, Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc., EMBO J., 15, 6595, 10.1002/j.1460-2075.1996.tb01050.x Perez-Roger, 1997, Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes., Oncogene., 14, 2373, 10.1038/sj.onc.1201197 Sheaff, 1997, Cyclin E-CDK2 is a regulator of p27Kip1., Genes Dev., 11, 1464, 10.1101/gad.11.11.1464 Vlach, 1997, Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27., EMBO J., 16, 5334, 10.1093/emboj/16.17.5334 Oberg, 1991, Interferon gamma abrogates the differentiation block in v-myc-expressing U-937 monoblasts., Proc Natl Acad Sci U S A., 88, 5567, 10.1073/pnas.88.13.5567 Steinman, 1998, Regulation of p21(WAF1) expression during normal myeloid differentiation., Blood., 91, 4531, 10.1182/blood.V91.12.4531 Casini, 1999, A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest., Oncogene., 18, 3235, 10.1038/sj.onc.1202630 Taniguchi, 1999, Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis., Blood., 93, 4167, 10.1182/blood.V93.12.4167 Yaroslavskiy, 1999, Subcellular and cell-cycle expression profiles of CDK-inhibitors in normal differentiating myeloid cells., Blood., 93, 2907, 10.1182/blood.V93.9.2907 Perez-Roger, 1999, Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)., EMBO J., 18, 5310, 10.1093/emboj/18.19.5310 Bouchard, 1999, Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27., EMBO J., 18, 5321, 10.1093/emboj/18.19.5321 Yang, 2001, Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc., Oncogene., 20, 1688, 10.1038/sj.onc.1204245 Furukawa, 2000, Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation., Br J Haematol., 110, 663, 10.1046/j.1365-2141.2000.02253.x Harbour, 1999, Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1., Cell., 98, 859, 10.1016/S0092-8674(00)81519-6 Lundberg, 1998, Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes., Mol Cell Biol., 18, 753, 10.1128/MCB.18.2.753 Bergh, 1997, Altered expression of the retinoblastoma tumor-suppressor gene in leukemic cell lines inhibits induction of differentiation but not G1-accumulation., Blood., 89, 2938, 10.1182/blood.V89.8.2938 Rots, 1999, Induced differentiation of U937 cells by 1,25-dihydroxyvitamin D3 involves cell cycle arrest in G1 that is preceded by a transient proliferative burst and an increase in cyclin expression., Blood., 93, 2721, 10.1182/blood.V93.8.2721 Liu, 1999, Elevated cyclin E levels, inactive retinoblastoma protein, and suppression of the p27(KIP1) inhibitor characterize early development of promyeloid cells into macrophages., Mol Cell Biol., 19, 6229, 10.1128/MCB.19.9.6229 May, 2001, Antisense suppression of p107 inhibits 3T3–L1 adipocyte differentiation., Biochem Biophys Res Commun., 283, 837, 10.1006/bbrc.2001.4886