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Các ưu tiên nghiên cứu về phục hồi chức năng và lão hóa với HIV: một khuôn khổ từ Hợp tác Nghiên cứu Quốc tế về HIV và Phục hồi chức năng Canada (CIHRRC)
Tóm tắt
Những người sống chung với HIV đang sống lâu hơn và có thể gặp phải những thách thức về thể chất, tâm lý và xã hội liên quan đến lão hóa và bệnh lý đồng mắc. Phục hồi chức năng có vị trí tốt để giải quyết những khuyết tật và tối đa hóa lão hóa khỏe mạnh. Một mạng lưới hợp tác quốc tế, mang tên Hợp tác Nghiên cứu Quốc tế về HIV và Phục hồi chức năng Canada (CIHRRC), hoạt động để định hướng cho lĩnh vực mới nổi này. Trong bài báo này, chúng tôi báo cáo các phát hiện từ mục tiêu của CIHRRC nhằm xác định các ưu tiên nghiên cứu nổi bật trong HIV, lão hóa và phục hồi chức năng từ các góc nhìn của những người sống chung với HIV, các bác sĩ, các nhà nghiên cứu, đại diện từ các tổ chức cộng đồng và các bên liên quan trong chính sách. Chúng tôi đã tiến hành một buổi tư vấn quốc tế đa bên liên quan với người sống chung với HIV, các nhà nghiên cứu, bác sĩ và đại diện của các tổ chức cộng đồng để xác định các ưu tiên nghiên cứu trong HIV, lão hóa và phục hồi chức năng. Các bên liên quan đã xác định các ưu tiên nghiên cứu trong một Diễn đàn Quốc tế kéo dài một ngày bao gồm các bài thuyết trình và thảo luận có điều phối. Chúng tôi đã thu thập và phân tích dữ liệu bằng các kỹ thuật phân tích nội dung, dẫn đến một khung các ưu tiên nghiên cứu. Sáu mươi chín bên liên quan từ các quốc gia bao gồm Canada (n=62; 90%), Vương quốc Anh (n=5; 7%), Hoa Kỳ (n=1; 1%) và Úc (n=1; 1%) đã tham gia Diễn đàn Quốc tế về Nghiên cứu HIV, Lão hóa và Phục hồi chức năng. Các bên liên quan đại diện cho các tổ chức cộng đồng (n=20; 29%), các cơ sở giáo dục (n=18; 26%), các tổ chức chăm sóc sức khỏe cộng đồng hoặc tổ chức (n=11; 16%), các tổ chức nghiên cứu hoặc sản xuất tri thức (n=10; 14%), và các tổ chức đại diện cho chính phủ hoặc ngành công nghiệp (n=10; 14%). Khung các ưu tiên nghiên cứu trong HIV, Lão hóa và Phục hồi chức năng bao gồm bảy ưu tiên nghiên cứu: (1) bản chất, quy mô và tác động của khuyết tật, các điều kiện sức khỏe đồng mắc và viêm mãn tính với HIV; (2) tỷ lệ, mức độ nghiêm trọng và tác động của sự yếu sức; (3) sự tham gia của cộng đồng và xã hội khi lão hóa với HIV; (4) các chiến lược quản lý bệnh mạn tính và lão hóa khỏe mạnh với HIV; (5) các yếu tố thuận lợi và cản trở tiếp cận và tham gia phục hồi chức năng; (6) hiệu quả của các can thiệp phục hồi chức năng cho lão hóa khỏe mạnh với HIV; và (7) thúc đẩy việc phát triển và sử dụng các biện pháp kết quả do bệnh nhân báo cáo trong HIV và lão hóa. Khung này nhấn mạnh các xem xét phương pháp để tiếp cận các ưu tiên và tầm quan trọng của chuyển giao và trao đổi tri thức để áp dụng kiến thức nghiên cứu vào thực tiễn, chương trình và chính sách. Những ưu tiên này cung cấp một nền tảng cho sự hợp tác giữa các nhóm quốc tế và đa ngành nhằm phát triển lĩnh vực HIV, lão hóa và phục hồi chức năng nhằm thúc đẩy lão hóa khỏe mạnh với HIV.
Từ khóa
#HIV #lão hóa #phục hồi chức năng #nghiên cứu quốc tế #bệnh lý đồng mắcTài liệu tham khảo
Collaboration Antiretroviral Therapy Cohort. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. 2008;372(9635):293–9 (Epub 2008/07/29).
Collaboration Antiretroviral Therapy Cohort. Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. The lancet HIV. 2017;4(8):e349–56.
Johnson LF, Mossong J, Dorrington RE, Schomaker M, Hoffmann CJ, Keiser O, et al. Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies. PLoS Med. 2013;10(4):e1001418 (Epub 2013/04/16).
Allavena C, Hanf M, Rey D, Duvivier C, BaniSadr F, Poizot-Martin I, et al. Antiretroviral exposure and comorbidities in an aging HIV-infected population: the challenge of geriatric patients. PLoS ONE. 2018;13(9):e0203895 (Epub 2018/09/22).
Autenrieth CS, Beck EJ, Stelzle D, Mallouris C, Mahy M, Ghys P. Global and regional trends of people living with HIV aged 50 and over: estimates and projections for 2000–2020. PLoS ONE. 2018;13(11):e0207005 (Epub 2018/11/30.).
Emlet CA, Fredriksen-Goldsen KI, Kim HJ, Jung H. Accounting for HIV health disparities: risk and protective factors among older gay and bisexual Men. J Aging Health. 2019:898264319848570. Epub 2019/05/14.
Bloch M. Frailty in people living with HIV. AIDS Res Ther. 2018;15(1):19 (Epub 2018/11/18).
Vance DE, Mugavero M, Willig J, Raper JL, Saag MS. Aging with HIV: a cross-sectional study of comorbidity prevalence and clinical characteristics across decades of life. J Assoc Nurses AIDS Care. 2011;22(1):17–25.
Guaraldi G, Malagoli A, Calcagno A, Mussi C, Celesia BM, Carli F, et al. The increasing burden and complexity of multi-morbidity and polypharmacy in geriatric HIV patients: a cross sectional study of people aged 65–74 years and more than 75 years. BMC Geriatr. 2018;18(1):99 (Epub 2018/04/22).
Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F, et al. HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology. 2011;75(23):2087–96 (Epub 2010/12/08).
Kendall CE, Wong J, Taljaard M, Glazier RH, Hogg W, Younger J, et al. A cross-sectional, population-based study measuring comorbidity among people living with HIV in Ontario. BMC public health. 2014;14(1):161 (Epub 2014/02/15).
Hasse B, Ledergerber B, Furrer H, Battegay M, Hirschel B, Cavassini M, et al. Morbidity and aging in HIV-infected persons: the Swiss HIV cohort study. Clin Infect Dis. 2011;53(11):1130–9 (Epub 2011/10/15).
Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120–6 (Epub 2011/10/15).
Sabin CA, Reiss P. Epidemiology of ageing with HIV: what can we learn from cohorts? Aids. 2017;31(Suppl 2):S121–8 (Epub 2017/05/05).
Myezwa H, Hanass-Hancock J, Ajidahun AT, Carpenter B. Disability and health outcomes—from a cohort of people on long-term anti-retroviral therapy. SAHARA J. 2018;15(1):50–9.
Hanass-Hancock J, Myezwa H, Carpenter B. Disability and living with HIV: baseline from a cohort of people on long term ART in South Africa. PLoS ONE. 2015;10(12):e0143936.
Havlik RJ, Brennan M, Karpiak SE. Comorbidities and depression in older adults with HIV. Sexual Health. 2011;8(4):551–9 (Epub 2011/12/01).
Shippy RA, Karpiak SE. The aging HIV/AIDS population: fragile social networks. Aging Ment Health. 2005;9(3):246–54.
Roger KS, Mignone J, Kirkland S. Social aspects of HIV/AIDS and aging: a thematic review. Can J Aging. 2013;32(3):298–306 (Epub 2013/08/15).
Siemon J, Blenkhorn L, Wilkins S, O’Brien KK, Solomon P. A grounded theory of social participation among older women living with HIV. Can J Occup Ther. 2013;80(4):241–50.
Emlet CA. “You’re awfully old to have this disease”: experiences of stigma and ageism in adults 50 years and older living with HIV/AIDS. Gerontologist. 2006;46(6):781–90 (Epub 2006/12/16).
O’Brien KK, Bayoumi AM, Strike C, Young NL, Davis AM. Exploring disability from the perspective of adults living with HIV/AIDS: development of a conceptual framework. Health Qual Life Outcomes. 2008;6:76 (Epub 2008/10/07).
Worthington C, Myers T, O’Brien K, Nixon S, Cockerill R. Rehabilitation in HIV/AIDS: development of an expanded conceptual framework. AIDS Patient Care STDS. 2005;19(4):258–71.
O’Brien KK, Solomon P, Trentham B, MacLachlan D, MacDermid J, Tynan AM, et al. Evidence-informed recommendations for rehabilitation with older adults living with HIV: a knowledge synthesis. BMJ Open. 2014;4(5):e004692 (Epub 2014/05/17).
Michel JP, Sadana R. “Healthy aging” concepts and measures. J Am Med Dir Assoc. 2017;18(6):460–4 (Epub 2017/05/10).
Emlet CA, Harris L, Furlotte C, Brennan DJ, Pierpaoli CM. ‘I’m happy in my life now, I’m a positive person’: approaches to successful ageing in older adults living with HIV in Ontario. Canada. Aging and Society. 2017;37(10):2128–51.
Joint United Nations Programme on HIV/AIDS (UNAIDS). 90-90-90: An ambitious treatment target to help end the AIDS epidemic. Geneva: UNAIDS; 2014.
Erdbeer G, Sabranski M, Sonntag I, Stoehr A, Horst HA, Plettenberg A, et al. Everything fine so far? Physical and mental health in HIV-infected patients with virological success and long-term exposure to antiretroviral therapy. J Int AIDS Soc. 2014;17:19673 (Epub 2014/11/15).
Lazarus JV, Safreed-Harmon K, Barton SE, Costagliola D, Dedes N, Del Amo Valero J, et al. Beyond viral suppression of HIV—the new quality of life frontier. BMC medicine. 2016;14(1):94 (Epub 2016/06/24).
Webster P. UNAIDS survey aligns with so-called fourth 90 for HIV/AIDS. Lancet. 2019;393(10187):P2188.
The Lancet H. Living well with HIV. The lancet HIV. 2019;6(12):e807 (Epub 2019/11/30).
deBoer H, Cudd S, Andrews M, Leung E, Petrie A, Chan Carusone S, et al. Recommendations for integrating physiotherapy into an interprofessional outpatient care setting for people living with HIV: a qualitative study. BMJ Open. 2019;9(5):e026827 (Epub 2019/05/28).
deBoer H, Andrews M, Cudd S, Leung E, Petrie A, Chan Carusone S, et al. Where and how does physical therapy fit? Integrating physical therapy into interprofessional HIV care. Disabil Rehabil. 2019;41(15):1768–77 (Epub 2018/03/14).
Galantino ML, McReynolds MA. Physical therapy management of HIV disease: a retrospective study. J Int Assoc Physicians AIDS Care. 1995;1(5):15–8.
Cobbing S, Hanass-Hancock J, Deane M. Physiotherapy rehabilitation in the context of HIV and disability in KwaZulu-Natal, South Africa. Disabil Rehabil. 2014;36(20):1687–94.
Pullen SD, Chigbo NN, Nwigwe EC, Chukwuka CJ, Amah CC, Idu SC. Physiotherapy intervention as a complementary treatment for people living with HIV/AIDS. HIV AIDS. 2014;6:99–107.
Brown D, Claffey A, Harding R. Evaluation of a physiotherapy-led group rehabilitation intervention for adults living with HIV: referrals, adherence and outcomes. AIDS Care. 2016;28(12):1495–505.
Kietrys DM, Galantino ML, Cohen ET, Parrott JS, Gould-Fogerite S, O’Brien KK. Yoga for persons living with HIV-related distal sensory polyneuropathy: a case series. Rehabil Oncol. 2018;36(2):123–31.
Worthington C, O’Brien K, Zack E, McKee E, Oliver B. Enhancing labour force participation for people living with HIV: a multi-perspective summary of the research evidence. AIDS Behav. 2012;16(1):231–43 (Epub 2011/06/28).
Worthington C, Myers T, O’Brien K, Nixon S, Cockerill R, Bereket T. Rehabilitation professionals and human immunodeficiency virus care: results of a national Canadian survey. Arch Phys Med Rehabil. 2008;89(1):105–13 (Epub 2008/01/01).
Burge E, Monnin D, Berchtold A, Allet L. Cost-effectiveness of physical therapy only and of usual care for various health conditions: systematic review. Phys Ther. 2016;96(6):774–86 (Epub 2015/12/19).
Turner-Stokes L, Dzingina M, Shavelle R, Bill A, Williams H, Sephton K. Estimated life-time savings in the cost of ongoing care following specialist rehabilitation for severe traumatic brain injury in the United Kingdom. J Head Trauma Rehabil. 2019;34(4):205–14 (Epub 2019/02/26).
Turner-Stokes L, Bavikatte G, Williams H, Bill A, Sephton K. Cost-efficiency of specialist hyperacute in-patient rehabilitation services for medically unstable patients with complex rehabilitation needs: a prospective cohort analysis. BMJ Open. 2016;6(9):e012112 (Epub 2016/09/10).
Turner-Stokes L, Williams H, Bill A, Bassett P, Sephton K. Cost-efficiency of specialist inpatient rehabilitation for working-aged adults with complex neurological disabilities: a multicentre cohort analysis of a national clinical data set. BMJ Open. 2016;6(2):e010238 (Epub 2016/02/26).
Shields GE, Wells A, Doherty P, Heagerty A, Buck D, Davies LM. Cost-effectiveness of cardiac rehabilitation: a systematic review. Heart. 2018;104(17):1403–10 (Epub 2018/04/15).
Edwards K, Jones N, Newton J, Foster C, Judge A, Jackson K, et al. The cost-effectiveness of exercise-based cardiac rehabilitation: a systematic review of the characteristics and methodological quality of published literature. Health economics review. 2017;7(1):37 (Epub 2017/10/21).
O’Brien KK, Solomon P, Ibáñez-Carrasco F, Chegwidden W, McDonnell E, Brown D, et al. Evolution of an International Research Collaborative in HIV and Rehabilitation: community engaged process, lessons learned, and recommendations. Prog Commun Health Partn. 2018;12(4):395–408.
O’Brien KK, Ibanez-Carrasco F, Solomon P, Harding R, Cattaneo J, Chegwidden W, et al. Advancing research and practice in HIV and rehabilitation: a framework of research priorities in HIV, disability and rehabilitation. BMC Infect Dis. 2014;14(1):3851 (Epub 2015/01/01).
Canadian Association for HIV Research (CAHR). Canadian Association for HIV Research (CAHR). https://www.cahr-acrvca/. 2020.
Realize. Strategic Plan 2019-2022. https://www.realizecanadaorg/wp-content/uploads/Realize-Strategic-Plan-2019-2022pdf. 2019.
Canada-United Kingdom HIV and Rehabilitation Research Collaborative (CUHRRC). 3rd International Forum on HIV and Rehabilitation Research. Advancing International Partnerships to Address Key Research Priorities in HIV and Rehabilitation (Final Report): Winnipeg, Canada. 2016. http://cuhrrc.hivandrehab.ca/docs/3rd-International-Forum-Final-Report-FINAL-CIRCULATED-Sept-2-16.pdf.
Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277–88 (Epub 2005/10/06).
Microsoft Corporation. Microsoft Excel. Microsoft Corporation; 2016.
Zicari S, Sessa L, Cotugno N, Ruggiero A, Morrocchi E, Concato C, et al. Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART. Viruses. 2019;11(3):200 (Epub 2019/03/02).
Nasi M, De Biasi S, Gibellini L, Bianchini E, Pecorini S, Bacca V, et al. Ageing and inflammation in patients with HIV infection. Clin Exp Immunol. 2017;187(1):44–52.
Deeks SG, Tracy R, Douek DC. Systemic effects of inflammation on health during chronic HIV infection. Immunity. 2013;39(4):633–45 (Epub 2013/10/22).
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146–56 (Epub 2001/03/17).
Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004;59(3):255–63 (Epub 2004/03/20).
Furlotte C, Schwartz K, Koornstra JJ, Naster R. ‘Got a room for me?’ Housing experiences of older adults living with HIV/AIDS in Ottawa. Can J Aging. 2012;31(1):37–48 (Epub 2012/02/22).
Pitts M, Grierson J, Misson S. Growing older with HIV: a study of health, social and economic circumstances for people Living with HIV in Australia over the age of 50 years. AIDS Patient Care STDS. 2005;19(7):460–5.
Liddy C, Johnston S, Guilcher S, Irving H, Hogel M, Jaglal S. Impact of a chronic disease self-management program on healthcare utilization in eastern Ontario, Canada. Prev Med Rep. 2015;2:586–90 (Epub 2016/02/05).
Pullen S. Physical therapy as non-pharmacological chronic pain management of adults living with HIV: self-reported pain scores and analgesic use. HIV/AIDS. 2017;9:177.
Nosrat S, Whitworth JW, Ciccolo JT. Exercise and mental health of people living with HIV: a systematic review. Chronic Illn. 2017;13(4):299–319 (Epub 2017/11/10).
Dixon G, Thornton EW, Young CA. Perceptions of self-efficacy and rehabilitation among neurologically disabled adults. Clin Rehabil. 2007;21(3):230–40 (Epub 2007/03/03).
Wojkowski S, Ahluwalia P, Radassao K, Wharin C, Walker G, Rushford N. Role-emerging clincial placements in a community-based HIV organization—opportunities for interprofessional collaboration: a case report. Physiother Can. 2019;71(4):384–90.
Solomon P, Salbach NM, O’Brien KK, Nixon S, Baxter L, Gervais N. Evaluation of a community-based self-management program to increase access to rehabilitation for people living with HIV. J Int Assoc Provid AIDS Care. 2019;18:2325958219883334 (Epub 2019/10/23).
Solomon P, Salbach N, O’Brien KK, Worthington C, Baxter L, Blanchard G, et al. Increasing capacity in rehabilitation in the management of HIV: a case-based e-mail intervention. Barcelona: AIDS Impact Conference; 2013.
Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173(5):489–95 (Epub 2005/09/01).
Searle SD, Mitnitski A, Gahbauer EA, Gill TM, Rockwood K. A standard procedure for creating a frailty index. BMC Geriatr. 2008;8:24 (Epub 2008/10/02).
O’Brien KK, Bayoumi AM, King K, Alexander R, Solomon P. Community engagement in health status instrument development: experience with the HIV disability questionnaire. Prog Commun Health Partn. 2014;8(4):549–59 (Epub 2014/01/01).
Travers R, Wilson MG, Flicker S, Guta A, Bereket T, McKay C, et al. The greater involvement of people living with AIDS principle: theory versus practice in Ontario’s HIV/AIDS community-based research sector. AIDS Care. 2008;20(6):615–24 (Epub 2008/06/26).
Solomon P, O’Brien KK, Baxter L, MacLachlan D, Robinson G. Community involvement in development of evidence-informed recommendations for rehabilitation for older adults living with HIV. Prog Community Health Partn. 2016;10(1):83–8.
Ibanez-Carrasco F, Watson JR, Tavares J. Supporting peer researchers: recommendations from our lived experience/expertise in community-based research in Canada. Harm Reduct J. 2019;16(1):55 (Epub 2019/09/05).
Canadian Instutites of Health Research (CIHR). Strategy for Patient-Oriented Research (SPOR). 2019 [cited 2019 September 20, 2019]; http://www.cihr-irsc.gc.ca/e/41204.html.
Canada-International HIV and Rehabilitation Research Collaborative (CIHRRC). 2019 [cited 2019 November 17, 2019]; http://cihrrc.hivandrehab.ca/.
Cobbing S, Hanass-Hancock J, Myezwa H. Home-based rehabilitation interventions for adults living with HIV: a scoping review. Af J AIDS Res. 2016;15(1):77–88.
Cobbing S, Hanass-Hancock J, Myezwa H. A home-based rehabilitation intervention for adults living with HIV: a randomized controlled trial. J Assoc Nurses AIDS Care. 2017;28(1):105–17.
Roos R, Myezwa H, van Aswegen H, Musenge E. Effects of an education and home-based pedometer walking program on ischemic heart disease risk factors in people infected with HIV: a randomized trial. J Acquir Immune Defic Syndr. 2014;67(3):268–76 (Epub 2014/08/21).
Chetty V, Hanass-Hancock J. A rehabilitation model as key to comprehensive care in the era of HIV as a chronic disease in South Africa. AIDS Care. 2016;28(Suppl 1):132–9.
Brothers TD, Kirkland S, Theou O, Zona S, Malagoli A, Wallace LMK, et al. Predictors of transitions in frailty severity and mortality among people aging with HIV. PLoS ONE. 2017;12(10):e0185352 (Epub 2017/10/06).
O’Brien KK, Davis AM, Strike C, Young NL, Bayoumi AM. Putting episodic disability into context: a qualitative study exploring factors that influence disability experienced by adults living with HIV/AIDS. J Int AIDS Soc. 2009;12(1):5 (Epub 2009/11/11).
Solomon P, O’Brien KK, Nixon S, Letts L, Baxter L, Gervais N. Trajectories of episodic disability in people aging with HIV: a Longitudinal Qualitative Study. J Int Assoc Provid AIDS Care. 2018;17:2325958218759210.
Solomon P, O’Brien K, Wilkins S, Gervais N. Aging with HIV and disability: the role of uncertainty. AIDS Care. 2014;26(2):240–5 (Epub 2013/06/27).
O’Brien KK, Hanna S, Solomon P, Worthington C, Ibanez-Carrasco F, Chan Carusone S, et al. Characterizing the disability experience among adults living with HIV: a structural equation model using the HIV disability questionnaire (HDQ) within the HIV, health and rehabilitation survey. BMC Infect Dis. 2019;19(1):594 (Epub 2019/07/10).
Solomon P, Letts L, O’Brien KK, Nixon S, Baxter L, Gervais N. ‘I’m still here, I’m still alive’: understanding successful aging in the context of HIV. Int J STD AIDS. 2018;29(2):172–7 (Epub 2017/07/22).
Solomon P, O’Brien K, Wilkins S, Gervais N. Aging with HIV: a model of disability. J Int Assoc Provid AIDS Care. 2014;13(6):519–25 (Epub 2014/08/26).
Rueda S, Chambers L, Wilson M, Mustard C, Rourke SB, Bayoumi A, et al. Association of returning to work with better health in working-aged adults: a systematic review. Am J Public Health. 2012;102(3):541–56 (Epub 2012/03/07).
Rueda S, Raboud J, Rourke SB, Bekele T, Bayoumi A, Lavis J, et al. Influence of employment and job security on physical and mental health in adults living with HIV: cross-sectional analysis. Open Med. 2012;6(4):e118–26 (Epub 2012/01/01).
Greene M, Hessol NA, Perissinotto C, Zepf R, Hutton Parrott A, Foreman C, et al. Loneliness in older adults living with HIV. AIDS Behav. 2018;22(5):1475–84 Epub 2017/11/21.
Furlotte C, Schwartz K. Mental health experiences of older adults living with HIV: uncertainty, stigma, and approaches to resilience. Can J Aging. 2017;36(2):125–40.
Emlet CA, Shiu C, Kim HJ, Fredriksen-Goldsen K. Bouncing back: resilience and mastery among HIV-positive older gay and bisexual men. Gerontologist. 2017;57(suppl 1):S40–9.
Bernardin KN, Toews DN, Restall GJ, Vuongphan L. Self-management interventions for people living with human immunodeficiency virus: a scoping review. Can J Occup Ther. 2013;80(5):314–27 (Epub 2014/03/20).
O’Brien KK, Dagenais M, Solomon P, Worthington C, Chan Carusone S, Ibanez-Carrasco F, et al. Use of living strategies among adults aging with HIV in Canada: comparison by age-group using data from the HIV, health and rehabilitation survey. J Int Assoc Provid AIDS Care. 2018;17:2325958218774041.
Heissel A, Zech P, Rapp MA, Schuch FB, Lawrence JB, Kangas M, et al. Effects of exercise on depression and anxiety in persons living with HIV: a meta-analysis. J Psychosom Res. 2019;126:109823 (Epub 2019/09/14).
Vancampfort D, Mugisha J, De Hert M, Probst M, Firth J, Gorczynski P, et al. Global physical activity levels among people living with HIV: a systematic review and meta-analysis. Disabil Rehabil. 2018;40(4):388–97 (Epub 2016/12/09).
O’Brien KK, Tynan AM, Nixon SA, Glazier RH. Effectiveness of Progressive Resistive Exercise (PRE) in the context of HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol. BMC Infect Dis. 2017;17(1):268.
O’Brien KK, Tynan AM, Nixon SA, Glazier RH. Effectiveness of aerobic exercise for adults living with HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol. BMC Infect Dis. 2016;16(1):182.
O’Brien KK, Bayoumi AM, Solomon P, Tang A, Murzin K, Chan Carusone S, et al. Evaluating a community-based exercise intervention with adults living with HIV: protocol for an interrupted time series study. BMJ Open. 2016;6(10):e013618 (Epub 2016/11/01).
Quigley A, O’Brien KK, Brouillette MJ, MacKay-Lyons M. Evaluating the feasibility and impact of a yoga intervention on cognition, physical function, physical activity, and affective outcomes in people living with HIV: protocol for a Randomized Pilot Trial. JMIR Res Protoc. 2019;8(5):e13818 (Epub 2019/05/23).
Greene M, Justice A, Covinsky KE. Assessment of geriatric syndromes and physical function in people living with HIV. Virulence. 2017;8(5):586–98.
Piggott DA, Erlandson KM, Yarasheski KE. Frailty in HIV: epidemiology, biology, measurement, interventions, and research needs. Curr HIV/AIDS Rep. 2016;13(6):340–8 (Epub 2016/08/24).
Brothers TD, Kirkland S, Guaraldi G, Falutz J, Theou O, Johnston BL, et al. Frailty in people aging with human immunodeficiency virus (HIV) infection. J Infect Dis. 2014;210(8):1170–9 (Epub 2014/06/07).
European AIDS Clinical Society (EACS). European AIDS Clinical Society (EACS) Guidelines, Version 10.0. London: European AIDS Clinical Society (EACS); 2019. p. 2019.
Kall M, Marcellin F, Harding R, Lazarus JV, Carrieri P. Patient-reported outcomes to enhance person-centred HIV care. Lancet HIV. 2019;7(1):e59–68 (Epub 2019/11/30).
Engler K, Lessard D, Lebouche B. A Review of HIV-Specific Patient-Reported Outcome Measures. The patient. 2017;10(2):187–202 Epub 2016/09/18.
O’Brien KK, Solomon P, Bergin C, O’Dea S, Stratford P, Iku N, et al. Reliability and validity of a new HIV-specific questionnaire with adults living with HIV in Canada and Ireland: the HIV Disability Questionnaire (HDQ). Health Qual Life Outcomes. 2015;13:124.
Brown DA, Simmons B, Boffito M, Aubry R, Nwokolo N, Harding R, et al. Evaluation of the psychometric properties of the HIV Disability Questionnaire among adults living with HIV in the United Kingdom: a cross-sectional self-report measurement study. PLoS ONE. 2019;14(7):e0213222 (Epub 2019/07/11).
O’Brien KK, Kietrys D, Galantino ML, Parrott JS, Davis T, Tran Q, et al. Reliability and validity of the HIV Disability Questionnaire (HDQ) with adults living with HIV in the United States. J Int Assoc Provid AIDS Care. 2019;18:2325958219888461 (Epub 2019/11/27).
Fredericksen RJ, Fitzsimmons E, Gibbons LE, Loo S, Dougherty S, Avendano-Soto S, et al. How do treatment priorities differ between patients in HIV care and their providers? A Mixed-Methods Study. AIDS Behav. 2019;24(4):1170–80 (Epub 2019/12/14).
Rankin NM, McGregor D, Butow PN, White K, Phillips JL, Young JM, et al. Adapting the nominal group technique for priority setting of evidence-practice gaps in implementation science. BMC Med Res Methodol. 2016;16(1):110 (Epub 2016/08/28).
Cobbing S, Chetty V, Hanass-Hancock J, Jelsma J, Myezwa H, Nixon SA. Position paper: the essential role of physiotherapist in providing rehabilitation services to people living with HIV in South Africa. South Afr J Physiother. 2017;69(1):22–5.
Ibanez-Carrasco F, Terpstra A, Rourke S, Yamamoto A, Chan Carusone S, Baltzer Turje R, et al. Creating productive tensions: clinicians working with patients as peer researchers in a community-based participatory research study of the lived experience of HIV-associated neurocognitive disorder (HAND). Can J Action Res. 2018;19(3):53–72.