Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy

Arida, 1999, The course of untreated seizures in the pilocarpine model of epilepsy, Epilepsy Res., 34, 99, 10.1016/S0920-1211(98)00092-8

Cavalheiro, 1991, Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures, Epilepsia, 32, 778, 10.1111/j.1528-1157.1991.tb05533.x

Clifford, 1987, The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures, Neuroscience, 23, 953, 10.1016/0306-4522(87)90171-0

Ebert, 1999, Effect of unspecific and caspase-3 specific caspase inhibitors in the kainate model of temporal lobe epilepsy, Epilepsia, 40, 10

Goodman, 1998, Experimental models of status epilepticus, 95

Hellier, 1998, Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy, Epilepsy Res., 31, 73, 10.1016/S0920-1211(98)00017-5

Honchar, 1983, Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats, Science, 220, 323, 10.1126/science.6301005

Jope, 1986, Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats, Exp. Neurol., 91, 471, 10.1016/0014-4886(86)90045-2

Krupp, 1998, Anticonvulsant drug effects in the direct cortical ramp-stimulation model in rats: Comparison with conventional seizure models, J. Pharmacol. Exp. Ther., 285, 1137

Leite, 1995, Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats, Epilepsy Res., 20, 93, 10.1016/0920-1211(94)00070-D

Lemos, 1995, Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats, Exp. Brain Res., 102, 423, 10.1007/BF00230647

Löscher, 1986, Is amygdala kindling in rats a model for drug-resistant partial epilepsy?, Exp. Neurol., 93, 211, 10.1016/0014-4886(86)90160-3

Persinger, 1993, Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine, Physiol. Behav., 53, 849, 10.1016/0031-9384(93)90261-D

Racine, 1972, Modification of seizure activity by electrical stimulation: II. Motor seizure, Electroencephalogr. Clin. Neurophysiol., 32, 281, 10.1016/0013-4694(72)90177-0

Turski, 1989, Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: A novel model of intractable epilepsy, Synapse, 3, 154, 10.1002/syn.890030207

Turski, 1983, Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study, Behav. Brain Res., 9, 315, 10.1016/0166-4328(83)90136-5

Vanneste-Goemaere, 1999, Electrophysiological and neuropathological changes resulting from pilocarpine-induced epileptogenesis in the rat: dependence on seizure duration, Epilepsia, 40, 38